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NSAIDs inhibit tumorigenesis, but how?
Gurpinar E, Grizzle WE, Piazza GA. Gurpinar E, et al. Among authors: piazza ga. Clin Cancer Res. 2014 Mar 1;20(5):1104-13. doi: 10.1158/1078-0432.CCR-13-1573. Epub 2013 Dec 5. Clin Cancer Res. 2014. PMID: 24311630 Free PMC article. Review.
A novel sulindac derivative that does not inhibit cyclooxygenases but potently inhibits colon tumor cell growth and induces apoptosis with antitumor activity.
Piazza GA, Keeton AB, Tinsley HN, Gary BD, Whitt JD, Mathew B, Thaiparambil J, Coward L, Gorman G, Li Y, Sani B, Hobrath JV, Maxuitenko YY, Reynolds RC. Piazza GA, et al. Cancer Prev Res (Phila). 2009 Jun;2(6):572-80. doi: 10.1158/1940-6207.CAPR-09-0001. Epub 2009 May 26. Cancer Prev Res (Phila). 2009. PMID: 19470791 Free PMC article.
Colon tumor cell growth-inhibitory activity of sulindac sulfide and other nonsteroidal anti-inflammatory drugs is associated with phosphodiesterase 5 inhibition.
Tinsley HN, Gary BD, Thaiparambil J, Li N, Lu W, Li Y, Maxuitenko YY, Keeton AB, Piazza GA. Tinsley HN, et al. Among authors: piazza ga. Cancer Prev Res (Phila). 2010 Oct;3(10):1303-13. doi: 10.1158/1940-6207.CAPR-10-0030. Epub 2010 Sep 28. Cancer Prev Res (Phila). 2010. PMID: 20876730 Free PMC article.
A novel sulindac derivative that potently suppresses colon tumor cell growth by inhibiting cGMP phosphodiesterase and β-catenin transcriptional activity.
Whitt JD, Li N, Tinsley HN, Chen X, Zhang W, Li Y, Gary BD, Keeton AB, Xi Y, Abadi AH, Grizzle WE, Piazza GA. Whitt JD, et al. Among authors: piazza ga. Cancer Prev Res (Phila). 2012 Jun;5(6):822-33. doi: 10.1158/1940-6207.CAPR-11-0559. Epub 2012 May 3. Cancer Prev Res (Phila). 2012. PMID: 22556201 Free PMC article.
New NSAID targets and derivatives for colorectal cancer chemoprevention.
Tinsley HN, Grizzle WE, Abadi A, Keeton A, Zhu B, Xi Y, Piazza GA. Tinsley HN, et al. Among authors: piazza ga. Recent Results Cancer Res. 2013;191:105-20. doi: 10.1007/978-3-642-30331-9_6. Recent Results Cancer Res. 2013. PMID: 22893202 Free PMC article. Review.
Sulindac sulfide inhibits sarcoendoplasmic reticulum Ca2+ ATPase, induces endoplasmic reticulum stress response, and exerts toxicity in glioma cells: relevant similarities to and important differences from celecoxib.
White MC, Johnson GG, Zhang W, Hobrath JV, Piazza GA, Grimaldi M. White MC, et al. Among authors: piazza ga. J Neurosci Res. 2013 Mar;91(3):393-406. doi: 10.1002/jnr.23169. Epub 2012 Dec 30. J Neurosci Res. 2013. PMID: 23280445 Free PMC article.
MicroRNA and cancer chemoprevention.
Yi B, Piazza GA, Su X, Xi Y. Yi B, et al. Among authors: piazza ga. Cancer Prev Res (Phila). 2013 May;6(5):401-9. doi: 10.1158/1940-6207.CAPR-13-0032. Epub 2013 Mar 26. Cancer Prev Res (Phila). 2013. PMID: 23531448 Free PMC article. Review.
134 results