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High-throughput Oligopaint screen identifies druggable 3D genome regulators.
Park DS, Nguyen SC, Isenhart R, Shah PP, Kim W, Barnett RJ, Chandra A, Luppino JM, Harke J, Wai M, Walsh PJ, Abdill RJ, Yang R, Lan Y, Yoon S, Yunker R, Kanemaki MT, Vahedi G, Phillips-Cremins JE, Jain R, Joyce EF. Park DS, et al. Among authors: phillips cremins je. Nature. 2023 Aug;620(7972):209-217. doi: 10.1038/s41586-023-06340-w. Epub 2023 Jul 12. Nature. 2023. PMID: 37438531
An integrated multi-omic analysis of iPSC-derived motor neurons from C9ORF72 ALS patients.
NeuroLINCS Consortium; Li J, Lim RG, Kaye JA, Dardov V, Coyne AN, Wu J, Milani P, Cheng A, Thompson TG, Ornelas L, Frank A, Adam M, Banuelos MG, Casale M, Cox V, Escalante-Chong R, Daigle JG, Gomez E, Hayes L, Holewenski R, Lei S, Lenail A, Lima L, Mandefro B, Matlock A, Panther L, Patel-Murray NL, Pham J, Ramamoorthy D, Sachs K, Shelley B, Stocksdale J, Trost H, Wilhelm M, Venkatraman V, Wassie BT, Wyman S, Yang S; NYGC ALS Consortium; Van Eyk JE, Lloyd TE, Finkbeiner S, Fraenkel E, Rothstein JD, Sareen D, Svendsen CN, Thompson LM. NeuroLINCS Consortium, et al. iScience. 2021 Oct 12;24(11):103221. doi: 10.1016/j.isci.2021.103221. eCollection 2021 Nov 19. iScience. 2021. PMID: 34746695 Free PMC article.
Detecting hierarchical genome folding with network modularity.
Norton HK, Emerson DJ, Huang H, Kim J, Titus KR, Gu S, Bassett DS, Phillips-Cremins JE. Norton HK, et al. Nat Methods. 2018 Feb;15(2):119-122. doi: 10.1038/nmeth.4560. Epub 2018 Jan 15. Nat Methods. 2018. PMID: 29334377 Free PMC article.
LADL: light-activated dynamic looping for endogenous gene expression control.
Kim JH, Rege M, Valeri J, Dunagin MC, Metzger A, Titus KR, Gilgenast TG, Gong W, Beagan JA, Raj A, Phillips-Cremins JE. Kim JH, et al. Nat Methods. 2019 Jul;16(7):633-639. doi: 10.1038/s41592-019-0436-5. Epub 2019 Jun 24. Nat Methods. 2019. PMID: 31235883 Free PMC article.
Chromatin structure dynamics during the mitosis-to-G1 phase transition.
Zhang H, Emerson DJ, Gilgenast TG, Titus KR, Lan Y, Huang P, Zhang D, Wang H, Keller CA, Giardine B, Hardison RC, Phillips-Cremins JE, Blobel GA. Zhang H, et al. Nature. 2019 Dec;576(7785):158-162. doi: 10.1038/s41586-019-1778-y. Epub 2019 Nov 27. Nature. 2019. PMID: 31776509 Free PMC article.
Alteration of genome folding via contact domain boundary insertion.
Zhang D, Huang P, Sharma M, Keller CA, Giardine B, Zhang H, Gilgenast TG, Phillips-Cremins JE, Hardison RC, Blobel GA. Zhang D, et al. Nat Genet. 2020 Oct;52(10):1076-1087. doi: 10.1038/s41588-020-0680-8. Epub 2020 Aug 31. Nat Genet. 2020. PMID: 32868908 Free PMC article.
Cohesin-mediated loop anchors confine the locations of human replication origins.
Emerson DJ, Zhao PA, Cook AL, Barnett RJ, Klein KN, Saulebekova D, Ge C, Zhou L, Simandi Z, Minsk MK, Titus KR, Wang W, Gong W, Zhang D, Yang L, Venev SV, Gibcus JH, Yang H, Sasaki T, Kanemaki MT, Yue F, Dekker J, Chen CL, Gilbert DM, Phillips-Cremins JE. Emerson DJ, et al. Among authors: phillips cremins je. Nature. 2022 Jun;606(7915):812-819. doi: 10.1038/s41586-022-04803-0. Epub 2022 Jun 8. Nature. 2022. PMID: 35676475 Free PMC article.
44 results