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IRIS: Discovery of cancer immunotherapy targets arising from pre-mRNA alternative splicing.
Pan Y, Phillips JW, Zhang BD, Noguchi M, Kutschera E, McLaughlin J, Nesterenko PA, Mao Z, Bangayan NJ, Wang R, Tran W, Yang HT, Wang Y, Xu Y, Obusan MB, Cheng D, Lee AH, Kadash-Edmondson KE, Champhekar A, Puig-Saus C, Ribas A, Prins RM, Seet CS, Crooks GM, Witte ON, Xing Y. Pan Y, et al. Among authors: phillips jw. Proc Natl Acad Sci U S A. 2023 May 23;120(21):e2221116120. doi: 10.1073/pnas.2221116120. Epub 2023 May 16. Proc Natl Acad Sci U S A. 2023. PMID: 37192158 Free PMC article.
N-Myc Drives Neuroendocrine Prostate Cancer Initiated from Human Prostate Epithelial Cells.
Lee JK, Phillips JW, Smith BA, Park JW, Stoyanova T, McCaffrey EF, Baertsch R, Sokolov A, Meyerowitz JG, Mathis C, Cheng D, Stuart JM, Shokat KM, Gustafson WC, Huang J, Witte ON. Lee JK, et al. Among authors: phillips jw. Cancer Cell. 2016 Apr 11;29(4):536-547. doi: 10.1016/j.ccell.2016.03.001. Epub 2016 Mar 31. Cancer Cell. 2016. PMID: 27050099 Free PMC article.
Deep-learning augmented RNA-seq analysis of transcript splicing.
Zhang Z, Pan Z, Ying Y, Xie Z, Adhikari S, Phillips J, Carstens RP, Black DL, Wu Y, Xing Y. Zhang Z, et al. Nat Methods. 2019 Apr;16(4):307-310. doi: 10.1038/s41592-019-0351-9. Epub 2019 Mar 25. Nat Methods. 2019. PMID: 30923373 Free PMC article.
RNA Dysregulation: An Expanding Source of Cancer Immunotherapy Targets.
Pan Y, Kadash-Edmondson KE, Wang R, Phillips J, Liu S, Ribas A, Aplenc R, Witte ON, Xing Y. Pan Y, et al. Trends Pharmacol Sci. 2021 Apr;42(4):268-282. doi: 10.1016/j.tips.2021.01.006. Trends Pharmacol Sci. 2021. PMID: 33711255 Free PMC article. Review.
HLA-A∗02:01 restricted T cell receptors against the highly conserved SARS-CoV-2 polymerase cross-react with human coronaviruses.
Nesterenko PA, McLaughlin J, Tsai BL, Burton Sojo G, Cheng D, Zhao D, Mao Z, Bangayan NJ, Obusan MB, Su Y, Ng RH, Chour W, Xie J, Li YR, Lee D, Noguchi M, Carmona C, Phillips JW, Kim JT, Yang L, Heath JR, Boutros PC, Witte ON. Nesterenko PA, et al. Among authors: phillips jw. Cell Rep. 2021 Dec 28;37(13):110167. doi: 10.1016/j.celrep.2021.110167. Epub 2021 Dec 10. Cell Rep. 2021. PMID: 34919800 Free PMC article.
Physical and in silico immunopeptidomic profiling of a cancer antigen prostatic acid phosphatase reveals targets enabling TCR isolation.
Mao Z, Nesterenko PA, McLaughlin J, Deng W, Burton Sojo G, Cheng D, Noguchi M, Chour W, DeLucia DC, Finton KA, Qin Y, Obusan MB, Tran W, Wang L, Bangayan NJ, Ta L, Chen CC, Seet CS, Crooks GM, Phillips JW, Heath JR, Strong RK, Lee JK, Wohlschlegel JA, Witte ON. Mao Z, et al. Among authors: phillips jw. Proc Natl Acad Sci U S A. 2022 Aug 2;119(31):e2203410119. doi: 10.1073/pnas.2203410119. Epub 2022 Jul 25. Proc Natl Acad Sci U S A. 2022. PMID: 35878026 Free PMC article.
143 results