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Cardiac Late Sodium Channel Current Is a Molecular Target for the Sodium/Glucose Cotransporter 2 Inhibitor Empagliflozin.
Philippaert K, Kalyaanamoorthy S, Fatehi M, Long W, Soni S, Byrne NJ, Barr A, Singh J, Wong J, Palechuk T, Schneider C, Darwesh AM, Maayah ZH, Seubert JM, Barakat K, Dyck JRB, Light PE. Philippaert K, et al. Circulation. 2021 Jun;143(22):2188-2204. doi: 10.1161/CIRCULATIONAHA.121.053350. Epub 2021 Apr 9. Circulation. 2021. PMID: 33832341 Free PMC article.
Steviol glycosides enhance pancreatic beta-cell function and taste sensation by potentiation of TRPM5 channel activity.
Philippaert K, Pironet A, Mesuere M, Sones W, Vermeiren L, Kerselaers S, Pinto S, Segal A, Antoine N, Gysemans C, Laureys J, Lemaire K, Gilon P, Cuypers E, Tytgat J, Mathieu C, Schuit F, Rorsman P, Talavera K, Voets T, Vennekens R. Philippaert K, et al. Nat Commun. 2017 Mar 31;8:14733. doi: 10.1038/ncomms14733. Nat Commun. 2017. PMID: 28361903 Free PMC article.
TRPM4-dependent post-synaptic depolarization is essential for the induction of NMDA receptor-dependent LTP in CA1 hippocampal neurons.
Menigoz A, Ahmed T, Sabanov V, Philippaert K, Pinto S, Kerselaers S, Segal A, Freichel M, Voets T, Nilius B, Vennekens R, Balschun D. Menigoz A, et al. Among authors: philippaert k. Pflugers Arch. 2016 Apr;468(4):593-607. doi: 10.1007/s00424-015-1764-7. Epub 2015 Dec 3. Pflugers Arch. 2016. PMID: 26631168 Free PMC article.
TRPM5 in the battle against diabetes and obesity.
Vennekens R, Mesuere M, Philippaert K. Vennekens R, et al. Among authors: philippaert k. Acta Physiol (Oxf). 2018 Feb;222(2). doi: 10.1111/apha.12949. Epub 2017 Oct 4. Acta Physiol (Oxf). 2018. PMID: 28834354 Review.
Continuous glucose monitoring during pregnancy in healthy mice.
Wuyts C, Simoens C, Pinto S, Philippaert K, Vennekens R. Wuyts C, et al. Among authors: philippaert k. Sci Rep. 2021 Feb 24;11(1):4450. doi: 10.1038/s41598-021-83901-x. Sci Rep. 2021. PMID: 33627830 Free PMC article.
21 results