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Cancer therapy shapes the fitness landscape of clonal hematopoiesis.
Bolton KL, Ptashkin RN, Gao T, Braunstein L, Devlin SM, Kelly D, Patel M, Berthon A, Syed A, Yabe M, Coombs CC, Caltabellotta NM, Walsh M, Offit K, Stadler Z, Mandelker D, Schulman J, Patel A, Philip J, Bernard E, Gundem G, Ossa JEA, Levine M, Martinez JSM, Farnoud N, Glodzik D, Li S, Robson ME, Lee C, Pharoah PDP, Stopsack KH, Spitzer B, Mantha S, Fagin J, Boucai L, Gibson CJ, Ebert BL, Young AL, Druley T, Takahashi K, Gillis N, Ball M, Padron E, Hyman DM, Baselga J, Norton L, Gardos S, Klimek VM, Scher H, Bajorin D, Paraiso E, Benayed R, Arcila ME, Ladanyi M, Solit DB, Berger MF, Tallman M, Garcia-Closas M, Chatterjee N, Diaz LA Jr, Levine RL, Morton LM, Zehir A, Papaemmanuil E. Bolton KL, et al. Among authors: philip j. Nat Genet. 2020 Nov;52(11):1219-1226. doi: 10.1038/s41588-020-00710-0. Epub 2020 Oct 26. Nat Genet. 2020. PMID: 33106634 Free PMC article.
Chemotherapy and COVID-19 Outcomes in Patients With Cancer.
Jee J, Foote MB, Lumish M, Stonestrom AJ, Wills B, Narendra V, Avutu V, Murciano-Goroff YR, Chan JE, Derkach A, Philip J, Belenkaya R, Kerpelev M, Maloy M, Watson A, Fong C, Janjigian Y, Diaz LA Jr, Bolton KL, Pessin MS. Jee J, et al. Among authors: philip j. J Clin Oncol. 2020 Oct 20;38(30):3538-3546. doi: 10.1200/JCO.20.01307. Epub 2020 Aug 14. J Clin Oncol. 2020. PMID: 32795225 Free PMC article.
Real-World Outcomes of an Automated Physician Support System for Genome-Driven Oncology.
Tao JJ, Eubank MH, Schram AM, Cangemi N, Pamer E, Rosen EY, Schultz N, Chakravarty D, Philip J, Hechtman JF, Harding JJ, Smyth LM, Jhaveri KL, Drilon A, Ladanyi M, Solit DB, Zehir A, Berger MF, Stetson PD, Gardos SM, Hyman DM. Tao JJ, et al. Among authors: philip j. JCO Precis Oncol. 2019 Jul 24;3:PO.19.00066. doi: 10.1200/PO.19.00066. eCollection 2019. JCO Precis Oncol. 2019. PMID: 32914018 Free PMC article.
Interplay between chromosomal alterations and gene mutations shapes the evolutionary trajectory of clonal hematopoiesis.
Gao T, Ptashkin R, Bolton KL, Sirenko M, Fong C, Spitzer B, Menghrajani K, Ossa JEA, Zhou Y, Bernard E, Levine M, Martinez JSM, Zhang Y, Franch-Expósito S, Patel M, Braunstein LZ, Kelly D, Yabe M, Benayed R, Caltabellotta NM, Philip J, Paraiso E, Mantha S, Solit DB, Diaz LA Jr, Berger MF, Klimek V, Levine RL, Zehir A, Devlin SM, Papaemmanuil E. Gao T, et al. Among authors: philip j. Nat Commun. 2021 Jan 12;12(1):338. doi: 10.1038/s41467-020-20565-7. Nat Commun. 2021. PMID: 33436578 Free PMC article.
Inhibition of circulating dipeptidyl peptidase 4 activity in patients with metastatic prostate cancer.
Nazarian A, Lawlor K, Yi SS, Philip J, Ghosh M, Yaneva M, Villanueva J, Saghatelian A, Assel M, Vickers AJ, Eastham JA, Scher HI, Carver BS, Lilja H, Tempst P. Nazarian A, et al. Among authors: philip j. Mol Cell Proteomics. 2014 Nov;13(11):3082-96. doi: 10.1074/mcp.M114.038836. Epub 2014 Jul 23. Mol Cell Proteomics. 2014. PMID: 25056937 Free PMC article.
Genetic mechanisms of primary chemotherapy resistance in pediatric acute myeloid leukemia.
McNeer NA, Philip J, Geiger H, Ries RE, Lavallée VP, Walsh M, Shah M, Arora K, Emde AK, Robine N, Alonzo TA, Kolb EA, Gamis AS, Smith M, Gerhard DS, Guidry-Auvil J, Meshinchi S, Kentsis A. McNeer NA, et al. Among authors: philip j. Leukemia. 2019 Aug;33(8):1934-1943. doi: 10.1038/s41375-019-0402-3. Epub 2019 Feb 13. Leukemia. 2019. PMID: 30760869 Free PMC article.
Comparison of therapy-related and de novo core binding factor acute myeloid leukemia: A bone marrow pathology group study.
Rogers HJ, Wang X, Xie Y, Davis AR, Thakral B, Wang SA, Borthakur G, Cantu MD, Margolskee EM, Philip JKS, Sukhanova M, Bagg A, Bueso-Ramos CE, Orazi A, Arber DA, Hsi ED, Hasserjian RP. Rogers HJ, et al. Among authors: philip jks. Am J Hematol. 2020 Jul;95(7):799-808. doi: 10.1002/ajh.25814. Epub 2020 Apr 20. Am J Hematol. 2020. PMID: 32249963 Free article. Clinical Trial.
Implications of Selection Bias Due to Delayed Study Entry in Clinical Genomic Studies.
Brown S, Lavery JA, Shen R, Martin AS, Kehl KL, Sweeney SM, Lepisto EM, Rizvi H, McCarthy CG, Schultz N, Warner JL, Park BH, Bedard PL, Riely GJ, Schrag D, Panageas KS; AACR Project GENIE Consortium. Brown S, et al. JAMA Oncol. 2022 Feb 1;8(2):287-291. doi: 10.1001/jamaoncol.2021.5153. JAMA Oncol. 2022. PMID: 34734967 Free PMC article.
Differential exoprotease activities confer tumor-specific serum peptidome patterns.
Villanueva J, Shaffer DR, Philip J, Chaparro CA, Erdjument-Bromage H, Olshen AB, Fleisher M, Lilja H, Brogi E, Boyd J, Sanchez-Carbayo M, Holland EC, Cordon-Cardo C, Scher HI, Tempst P. Villanueva J, et al. Among authors: philip j. J Clin Invest. 2006 Jan;116(1):271-84. doi: 10.1172/JCI26022. J Clin Invest. 2006. PMID: 16395409 Free PMC article.
Correlation Between Surrogate End Points and Overall Survival in a Multi-institutional Clinicogenomic Cohort of Patients With Non-Small Cell Lung or Colorectal Cancer.
Kehl KL, Riely GJ, Lepisto EM, Lavery JA, Warner JL, LeNoue-Newton ML, Sweeney SM, Rudolph JE, Brown S, Yu C, Bedard PL, Schrag D, Panageas KS; American Association of Cancer Research (AACR) Project Genomics Evidence Neoplasia Information Exchange (GENIE) Consortium. Kehl KL, et al. JAMA Netw Open. 2021 Jul 1;4(7):e2117547. doi: 10.1001/jamanetworkopen.2021.17547. JAMA Netw Open. 2021. PMID: 34309669 Free PMC article.
1,053 results