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Targeting Wnt Signaling for the Treatment of Gastric Cancer.
Koushyar S, Powell AG, Vincan E, Phesse TJ. Koushyar S, et al. Among authors: phesse tj. Int J Mol Sci. 2020 May 30;21(11):3927. doi: 10.3390/ijms21113927. Int J Mol Sci. 2020. PMID: 32486243 Free PMC article. Review.
PHLDA1 expression marks the putative epithelial stem cells and contributes to intestinal tumorigenesis.
Sakthianandeswaren A, Christie M, D'Andreti C, Tsui C, Jorissen RN, Li S, Fleming NI, Gibbs P, Lipton L, Malaterre J, Ramsay RG, Phesse TJ, Ernst M, Jeffery RE, Poulsom R, Leedham SJ, Segditsas S, Tomlinson IP, Bernhard OK, Simpson RJ, Walker F, Faux MC, Church N, Catimel B, Flanagan DJ, Vincan E, Sieber OM. Sakthianandeswaren A, et al. Among authors: phesse tj. Cancer Res. 2011 May 15;71(10):3709-19. doi: 10.1158/0008-5472.CAN-10-2342. Epub 2011 May 10. Cancer Res. 2011. PMID: 21558389 Free article.
Partial inhibition of gp130-Jak-Stat3 signaling prevents Wnt-β-catenin-mediated intestinal tumor growth and regeneration.
Phesse TJ, Buchert M, Stuart E, Flanagan DJ, Faux M, Afshar-Sterle S, Walker F, Zhang HH, Nowell CJ, Jorissen R, Tan CW, Hirokawa Y, Eissmann MF, Poh AR, Malaterre J, Pearson HB, Kirsch DG, Provero P, Poli V, Ramsay RG, Sieber O, Burgess AW, Huszar D, Vincan E, Ernst M. Phesse TJ, et al. Sci Signal. 2014 Sep 30;7(345):ra92. doi: 10.1126/scisignal.2005411. Sci Signal. 2014. PMID: 25270258 Free article.
Frizzled7 functions as a Wnt receptor in intestinal epithelial Lgr5(+) stem cells.
Flanagan DJ, Phesse TJ, Barker N, Schwab RH, Amin N, Malaterre J, Stange DE, Nowell CJ, Currie SA, Saw JT, Beuchert E, Ramsay RG, Sansom OJ, Ernst M, Clevers H, Vincan E. Flanagan DJ, et al. Among authors: phesse tj. Stem Cell Reports. 2015 May 12;4(5):759-67. doi: 10.1016/j.stemcr.2015.03.003. Epub 2015 Apr 16. Stem Cell Reports. 2015. PMID: 25892522 Free PMC article.
Dual Targeting of Bromodomain and Extraterminal Domain Proteins, and WNT or MAPK Signaling, Inhibits c-MYC Expression and Proliferation of Colorectal Cancer Cells.
Tögel L, Nightingale R, Chueh AC, Jayachandran A, Tran H, Phesse T, Wu R, Sieber OM, Arango D, Dhillon AS, Dawson MA, Diez-Dacal B, Gahman TC, Filippakopoulos P, Shiau AK, Mariadason JM. Tögel L, et al. Mol Cancer Ther. 2016 Jun;15(6):1217-26. doi: 10.1158/1535-7163.MCT-15-0724. Epub 2016 Mar 16. Mol Cancer Ther. 2016. PMID: 26983878
46 results