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Functional interaction between PDGFβ and GluN2B-containing NMDA receptors in smooth muscle cell proliferation and migration in pulmonary arterial hypertension.
Quatredeniers M, Nakhleh MK, Dumas SJ, Courboulin A, Vinhas MC, Antigny F, Phan C, Guignabert C, Bendifallah I, Vocelle M, Fadel E, Dorfmüller P, Humbert M, Cohen-Kaminsky S. Quatredeniers M, et al. Among authors: phan c. Am J Physiol Lung Cell Mol Physiol. 2019 Mar 1;316(3):L445-L455. doi: 10.1152/ajplung.00537.2017. Epub 2018 Dec 13. Am J Physiol Lung Cell Mol Physiol. 2019. PMID: 30543306 Free article.
Increased pericyte coverage mediated by endothelial-derived fibroblast growth factor-2 and interleukin-6 is a source of smooth muscle-like cells in pulmonary hypertension.
Ricard N, Tu L, Le Hiress M, Huertas A, Phan C, Thuillet R, Sattler C, Fadel E, Seferian A, Montani D, Dorfmüller P, Humbert M, Guignabert C. Ricard N, et al. Among authors: phan c. Circulation. 2014 Apr 15;129(15):1586-97. doi: 10.1161/CIRCULATIONAHA.113.007469. Epub 2014 Jan 30. Circulation. 2014. PMID: 24481949
Proinflammatory Signature of the Dysfunctional Endothelium in Pulmonary Hypertension. Role of the Macrophage Migration Inhibitory Factor/CD74 Complex.
Le Hiress M, Tu L, Ricard N, Phan C, Thuillet R, Fadel E, Dorfmüller P, Montani D, de Man F, Humbert M, Huertas A, Guignabert C. Le Hiress M, et al. Among authors: phan c. Am J Respir Crit Care Med. 2015 Oct 15;192(8):983-97. doi: 10.1164/rccm.201402-0322OC. Am J Respir Crit Care Med. 2015. PMID: 26203495 Free article.
Therapeutic effect of pirfenidone in the sugen/hypoxia rat model of severe pulmonary hypertension.
Poble PB, Phan C, Quatremare T, Bordenave J, Thuillet R, Cumont A, Huertas A, Tu L, Dorfmüller P, Humbert M, Ghigna MR, Savale L, Guignabert C. Poble PB, et al. Among authors: phan c. FASEB J. 2019 Mar;33(3):3670-3679. doi: 10.1096/fj.201801659R. Epub 2018 Nov 27. FASEB J. 2019. PMID: 30481487 Free article.
PFD appears to be a potential therapy for PAH worthy of investigation and evaluation for clinical use in conjunction with current PAH treatments.-Poble, P.-B., Phan, C., Quatremare, T., Bordenave, J., Thuillet, R., Cumont, A., Huertas, A., Tu, L., Dorfmuller, P., Hu …
PFD appears to be a potential therapy for PAH worthy of investigation and evaluation for clinical use in conjunction with current PAH treatm …
Neutralization of CXCL12 attenuates established pulmonary hypertension in rats.
Bordenave J, Thuillet R, Tu L, Phan C, Cumont A, Marsol C, Huertas A, Savale L, Hibert M, Galzi JL, Bonnet D, Humbert M, Frossard N, Guignabert C. Bordenave J, et al. Among authors: phan c. Cardiovasc Res. 2020 Mar 1;116(3):686-697. doi: 10.1093/cvr/cvz153. Cardiovasc Res. 2020. PMID: 31173066
410 results