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Novel Insights into Pyrrolizidine Alkaloid Toxicity and Implications for Risk Assessment: Occurrence, Genotoxicity, Toxicokinetics, Risk Assessment-A Workshop Report.
Schrenk D, Fahrer J, Allemang A, Fu P, Lin G, Mahony C, Mulder PPJ, Peijnenburg A, Pfuhler S, Rietjens IMCM, Sachse B, Steinhoff B, These A, Troutman J, Wiesner J. Schrenk D, et al. Among authors: pfuhler s. Planta Med. 2022 Feb;88(2):98-117. doi: 10.1055/a-1646-3618. Epub 2021 Oct 29. Planta Med. 2022. PMID: 34715696 Free article.
Application of the adverse outcome pathway framework to genotoxic modes of action.
Sasaki JC, Allemang A, Bryce SM, Custer L, Dearfield KL, Dietz Y, Elhajouji A, Escobar PA, Fornace AJ Jr, Froetschl R, Galloway S, Hemmann U, Hendriks G, Li HH, Luijten M, Ouedraogo G, Peel L, Pfuhler S, Roberts DJ, Thybaud V, van Benthem J, Yauk CL, Schuler M. Sasaki JC, et al. Among authors: pfuhler s. Environ Mol Mutagen. 2020 Jan;61(1):114-134. doi: 10.1002/em.22339. Epub 2019 Oct 31. Environ Mol Mutagen. 2020. PMID: 31603995
A comparison of classical and 21st century genotoxicity tools: A proof of concept study of 18 chemicals comparing in vitro micronucleus, ToxTracker and genomics-based methods (TGx-DDI, whole genome clustering and connectivity mapping).
Allemang A, De Abrew KN, Shan YK, Krailler JM, Pfuhler S. Allemang A, et al. Among authors: pfuhler s. Environ Mol Mutagen. 2021 Feb;62(2):92-107. doi: 10.1002/em.22418. Epub 2020 Dec 7. Environ Mol Mutagen. 2021. PMID: 33252785 Free PMC article.
AOP report: Development of an adverse outcome pathway for oxidative DNA damage leading to mutations and chromosomal aberrations.
Cho E, Allemang A, Audebert M, Chauhan V, Dertinger S, Hendriks G, Luijten M, Marchetti F, Minocherhomji S, Pfuhler S, Roberts DJ, Trenz K, Yauk CL. Cho E, et al. Among authors: pfuhler s. Environ Mol Mutagen. 2022 Mar;63(3):118-134. doi: 10.1002/em.22479. Epub 2022 May 3. Environ Mol Mutagen. 2022. PMID: 35315142 Free PMC article.
75 results