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Page 1
Posttranslational Regulation of the Exon Skipping Machinery Controls Aberrant Splicing in Leukemia.
Zhou Y, Han C, Wang E, Lorch AH, Serafin V, Cho BK, Gutierrez Diaz BT, Calvo J, Fang C, Khodadadi-Jamayran A, Tabaglio T, Marier C, Kuchmiy A, Sun L, Yacu G, Filip SK, Jin Q, Takahashi YH, Amici DR, Rendleman EJ, Rawat R, Bresolin S, Paganin M, Zhang C, Li H, Kandela I, Politanska Y, Abdala-Valencia H, Mendillo ML, Zhu P, Palhais B, Van Vlierberghe P, Taghon T, Aifantis I, Goo YA, Guccione E, Heguy A, Tsirigos A, Wee KB, Mishra RK, Pflumio F, Accordi B, Basso G, Ntziachristos P. Zhou Y, et al. Among authors: pflumio f. Cancer Discov. 2020 Sep;10(9):1388-1409. doi: 10.1158/2159-8290.CD-19-1436. Epub 2020 May 22. Cancer Discov. 2020. PMID: 32444465 Free PMC article.
Genetic inactivation of the polycomb repressive complex 2 in T cell acute lymphoblastic leukemia.
Ntziachristos P, Tsirigos A, Van Vlierberghe P, Nedjic J, Trimarchi T, Flaherty MS, Ferres-Marco D, da Ros V, Tang Z, Siegle J, Asp P, Hadler M, Rigo I, De Keersmaecker K, Patel J, Huynh T, Utro F, Poglio S, Samon JB, Paietta E, Racevskis J, Rowe JM, Rabadan R, Levine RL, Brown S, Pflumio F, Dominguez M, Ferrando A, Aifantis I. Ntziachristos P, et al. Among authors: pflumio f. Nat Med. 2012 Feb 6;18(2):298-301. doi: 10.1038/nm.2651. Nat Med. 2012. PMID: 22237151 Free PMC article.
Triggering the TCR Developmental Checkpoint Activates a Therapeutically Targetable Tumor Suppressive Pathway in T-cell Leukemia.
Trinquand A, Dos Santos NR, Tran Quang C, Rocchetti F, Zaniboni B, Belhocine M, Da Costa de Jesus C, Lhermitte L, Tesio M, Dussiot M, Cosset FL, Verhoeyen E, Pflumio F, Ifrah N, Dombret H, Spicuglia S, Chatenoud L, Gross DA, Hermine O, Macintyre E, Ghysdael J, Asnafi V. Trinquand A, et al. Among authors: pflumio f. Cancer Discov. 2016 Sep;6(9):972-85. doi: 10.1158/2159-8290.CD-15-0675. Epub 2016 Jun 28. Cancer Discov. 2016. PMID: 27354269
Ontogenic Changes in Hematopoietic Hierarchy Determine Pediatric Specificity and Disease Phenotype in Fusion Oncogene-Driven Myeloid Leukemia.
Lopez CK, Noguera E, Stavropoulou V, Robert E, Aid Z, Ballerini P, Bilhou-Nabera C, Lapillonne H, Boudia F, Thirant C, Fagnan A, Arcangeli ML, Kinston SJ, Diop M, Job B, Lecluse Y, Brunet E, Babin L, Villeval JL, Delabesse E, Peters AHFM, Vainchenker W, Gaudry M, Masetti R, Locatelli F, Malinge S, Nerlov C, Droin N, Lobry C, Godin I, Bernard OA, Göttgens B, Petit A, Pflumio F, Schwaller J, Mercher T. Lopez CK, et al. Among authors: pflumio f. Cancer Discov. 2019 Dec;9(12):1736-1753. doi: 10.1158/2159-8290.CD-18-1463. Epub 2019 Oct 29. Cancer Discov. 2019. PMID: 31662298
Hypoxia favors chemoresistance in T-ALL through an HIF1α-mediated mTORC1 inhibition loop.
Fahy L, Calvo J, Chabi S, Renou L, Le Maout C, Poglio S, Leblanc T, Petit A, Baruchel A, Ballerini P, Naguibneva I, Haddad R, Arcangeli ML, Mazurier F, Pflumio F, Uzan B. Fahy L, et al. Among authors: pflumio f. Blood Adv. 2021 Jan 26;5(2):513-526. doi: 10.1182/bloodadvances.2020002832. Blood Adv. 2021. PMID: 33496749 Free PMC article.
β-Catenin and its new partner FOXO3 shake T-ALL.
Calvo J, Pflumio F. Calvo J, et al. Among authors: pflumio f. Blood. 2023 Mar 30;141(13):1503-1505. doi: 10.1182/blood.2022018650. Blood. 2023. PMID: 36995702 Free article. No abstract available.
NOTCH is a key regulator of human T-cell acute leukemia initiating cell activity.
Armstrong F, Brunet de la Grange P, Gerby B, Rouyez MC, Calvo J, Fontenay M, Boissel N, Dombret H, Baruchel A, Landman-Parker J, Roméo PH, Ballerini P, Pflumio F. Armstrong F, et al. Among authors: pflumio f. Blood. 2009 Feb 19;113(8):1730-40. doi: 10.1182/blood-2008-02-138172. Epub 2008 Nov 4. Blood. 2009. PMID: 18984862 Free article.
133 results