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Activated granulocytes and inflammatory cytokine signaling drive T-cell lymphoma progression and disease symptoms.
Jaeger A, Gambheer SMM, Sun X, Chernyakov D, Skorobohatko O, Mack T, Kissel S, Pfeifer D, Zeiser R, Fisch P, Andrieux G, Bräuer-Hartmann D, Bauer M, Schulze S, Follo M, Boerries M, von Bubnoff N, Miething C, Hidalgo JV, Klein C, Weber T, Wickenhauser C, Binder M, Dierks C. Jaeger A, et al. Among authors: pfeifer d. Blood. 2023 Jun 8;141(23):2824-2840. doi: 10.1182/blood.2022015653. Blood. 2023. PMID: 36696631
PIM kinases are essential for chronic lymphocytic leukemia cell survival (PIM2/3) and CXCR4-mediated microenvironmental interactions (PIM1).
Decker S, Finter J, Forde AJ, Kissel S, Schwaller J, Mack TS, Kuhn A, Gray N, Follo M, Jumaa H, Burger M, Zirlik K, Pfeifer D, Miduturu CV, Eibel H, Veelken H, Dierks C. Decker S, et al. Among authors: pfeifer d. Mol Cancer Ther. 2014 May;13(5):1231-45. doi: 10.1158/1535-7163.MCT-13-0575-T. Epub 2014 Mar 21. Mol Cancer Ther. 2014. PMID: 24659821
MiR-146a regulates the TRAF6/TNF-axis in donor T cells during GVHD.
Stickel N, Prinz G, Pfeifer D, Hasselblatt P, Schmitt-Graeff A, Follo M, Thimme R, Finke J, Duyster J, Salzer U, Zeiser R. Stickel N, et al. Among authors: pfeifer d. Blood. 2014 Oct 16;124(16):2586-95. doi: 10.1182/blood-2014-04-569046. Epub 2014 Sep 9. Blood. 2014. PMID: 25205119 Free article.
Therapeutic activity of multiple common γ-chain cytokine inhibition in acute and chronic GVHD.
Hechinger AK, Smith BA, Flynn R, Hanke K, McDonald-Hyman C, Taylor PA, Pfeifer D, Hackanson B, Leonhardt F, Prinz G, Dierbach H, Schmitt-Graeff A, Kovarik J, Blazar BR, Zeiser R. Hechinger AK, et al. Among authors: pfeifer d. Blood. 2015 Jan 15;125(3):570-80. doi: 10.1182/blood-2014-06-581793. Epub 2014 Oct 28. Blood. 2015. PMID: 25352130 Free PMC article.
The IL-33/ST2 axis augments effector T-cell responses during acute GVHD.
Reichenbach DK, Schwarze V, Matta BM, Tkachev V, Lieberknecht E, Liu Q, Koehn BH, Pfeifer D, Taylor PA, Prinz G, Dierbach H, Stickel N, Beck Y, Warncke M, Junt T, Schmitt-Graeff A, Nakae S, Follo M, Wertheimer T, Schwab L, Devlin J, Watkins SC, Duyster J, Ferrara JL, Turnquist HR, Zeiser R, Blazar BR. Reichenbach DK, et al. Among authors: pfeifer d. Blood. 2015 May 14;125(20):3183-92. doi: 10.1182/blood-2014-10-606830. Epub 2015 Mar 26. Blood. 2015. PMID: 25814531 Free PMC article.
275 results