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The α-synuclein PET tracer [18F] ACI-12589 distinguishes multiple system atrophy from other neurodegenerative diseases.
Smith R, Capotosti F, Schain M, Ohlsson T, Vokali E, Molette J, Touilloux T, Hliva V, Dimitrakopoulos IK, Puschmann A, Jögi J, Svenningsson P, Andréasson M, Sandiego C, Russell DS, Miranda-Azpiazu P, Halldin C, Stomrud E, Hall S, Bratteby K, Tampio L'Estrade E, Luthi-Carter R, Pfeifer A, Kosco-Vilbois M, Streffer J, Hansson O. Smith R, et al. Among authors: pfeifer a. Nat Commun. 2023 Oct 27;14(1):6750. doi: 10.1038/s41467-023-42305-3. Nat Commun. 2023. PMID: 37891183 Free PMC article.
Improved antibody pharmacokinetics by disruption of contiguous positive surface potential and charge reduction using alternate human framework.
Ollier R, Fuchs A, Gauye F, Piorkowska K, Menant S, Ratnam M, Montanari P, Guilhot F, Phillipe D, Audrain M, Egesipe AL, Névoltris D, Seredenina T, Pfeifer A, Kosco-Vilbois M, Afroz T. Ollier R, et al. Among authors: pfeifer a. MAbs. 2023 Jan-Dec;15(1):2232087. doi: 10.1080/19420862.2023.2232087. MAbs. 2023. PMID: 37408314 Free PMC article.
Targeting amyotrophic lateral sclerosis by neutralizing seeding-competent TDP-43 in CSF.
Audrain M, Egesipe AL, Tentillier N, Font L, Ratnam M, Mottier L, Clavel M, Le Roux-Bourdieu M, Fenyi A, Ollier R, Chevalier E, Guilhot F, Fuchs A, Piorkowska K, Carlyle B, Arnold SE, Berry JD, Luthi-Carter R, Adolfsson O, Pfeifer A, Kosco-Vilbois M, Seredenina T, Afroz T. Audrain M, et al. Among authors: pfeifer a. Brain Commun. 2023 Nov 3;5(6):fcad306. doi: 10.1093/braincomms/fcad306. eCollection 2023. Brain Commun. 2023. PMID: 38025276 Free PMC article.
Beneficial Effect of ACI-24 Vaccination on Aβ Plaque Pathology and Microglial Phenotypes in an Amyloidosis Mouse Model.
Rudan Njavro J, Vukicevic M, Fiorini E, Dinkel L, Müller SA, Berghofer A, Bordier C, Kozlov S, Halle A, Buschmann K, Capell A, Giudici C, Willem M, Feederle R, Lichtenthaler SF, Babolin C, Montanari P, Pfeifer A, Kosco-Vilbois M, Tahirovic S. Rudan Njavro J, et al. Among authors: pfeifer a. Cells. 2022 Dec 24;12(1):79. doi: 10.3390/cells12010079. Cells. 2022. PMID: 36611872 Free PMC article.
Immunotherapy targeting the C-terminal domain of TDP-43 decreases neuropathology and confers neuroprotection in mouse models of ALS/FTD.
Afroz T, Chevalier E, Audrain M, Dumayne C, Ziehm T, Moser R, Egesipe AL, Mottier L, Ratnam M, Neumann M, Havas D, Ollier R, Piorkowska K, Chauhan M, Silva AB, Thapa S, Stöhr J, Bavdek A, Eligert V, Adolfsson O, Nelson PT, Porta S, Lee VM, Pfeifer A, Kosco-Vilbois M, Seredenina T. Afroz T, et al. Among authors: pfeifer a. Neurobiol Dis. 2023 Apr;179:106050. doi: 10.1016/j.nbd.2023.106050. Epub 2023 Feb 20. Neurobiol Dis. 2023. PMID: 36809847 Free article.
Cold-induced expression of a truncated adenylyl cyclase 3 acts as rheostat to brown fat function.
Khani S, Topel H, Kardinal R, Tavanez AR, Josephrajan A, Larsen BDM, Gaudry MJ, Leyendecker P, Egedal NM, Güller AS, Stanic N, Ruppert PMM, Gaziano I, Hansmeier NR, Schmidt E, Klemm P, Vagliano LM, Stahl R, Duthie F, Krause JH, Bici A, Engelhard CA, Gohlke S, Frommolt P, Gnad T, Rada-Iglesias A, Pradas-Juni M, Schulz TJ, Wunderlich FT, Pfeifer A, Bartelt A, Jastroch M, Wachten D, Kornfeld JW. Khani S, et al. Among authors: pfeifer a. Nat Metab. 2024 Apr 29. doi: 10.1038/s42255-024-01033-8. Online ahead of print. Nat Metab. 2024. PMID: 38684889
[Benefits of participatory involvement of patients in the development of a dermatological treatment app-A report from the practice].
Koopmann A, Pfeifer AM, Schweickart L, Biniaminov N, Haas V, Marquardt P, Gößwein A, Czaban C, Biniaminov S, Blauth M, Glatzel C, Zimmermann C, Stork W, Olsavszky V, Schmieder A. Koopmann A, et al. Among authors: pfeifer am. Dermatologie (Heidelb). 2024 Mar 22. doi: 10.1007/s00105-024-05326-7. Online ahead of print. Dermatologie (Heidelb). 2024. PMID: 38517520 Review. German.
425 results