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FOXK1 and FOXK2 regulate aerobic glycolysis.
Sukonina V, Ma H, Zhang W, Bartesaghi S, Subhash S, Heglind M, Foyn H, Betz MJ, Nilsson D, Lidell ME, Naumann J, Haufs-Brusberg S, Palmgren H, Mondal T, Beg M, Jedrychowski MP, Taskén K, Pfeifer A, Peng XR, Kanduri C, Enerbäck S. Sukonina V, et al. Among authors: pfeifer a. Nature. 2019 Feb;566(7743):279-283. doi: 10.1038/s41586-019-0900-5. Epub 2019 Jan 30. Nature. 2019. PMID: 30700909
Adenosine activates brown adipose tissue and recruits beige adipocytes via A2A receptors.
Gnad T, Scheibler S, von Kügelgen I, Scheele C, Kilić A, Glöde A, Hoffmann LS, Reverte-Salisa L, Horn P, Mutlu S, El-Tayeb A, Kranz M, Deuther-Conrad W, Brust P, Lidell ME, Betz MJ, Enerbäck S, Schrader J, Yegutkin GG, Müller CE, Pfeifer A. Gnad T, et al. Among authors: pfeifer a. Nature. 2014 Dec 18;516(7531):395-9. doi: 10.1038/nature13816. Epub 2014 Oct 15. Nature. 2014. PMID: 25317558
The Gq signalling pathway inhibits brown and beige adipose tissue.
Klepac K, Kilić A, Gnad T, Brown LM, Herrmann B, Wilderman A, Balkow A, Glöde A, Simon K, Lidell ME, Betz MJ, Enerbäck S, Wess J, Freichel M, Blüher M, König G, Kostenis E, Insel PA, Pfeifer A. Klepac K, et al. Among authors: pfeifer a. Nat Commun. 2016 Mar 9;7:10895. doi: 10.1038/ncomms10895. Nat Commun. 2016. PMID: 26955961 Free PMC article.
Exosomal microRNA miR-92a concentration in serum reflects human brown fat activity.
Chen Y, Buyel JJ, Hanssen MJ, Siegel F, Pan R, Naumann J, Schell M, van der Lans A, Schlein C, Froehlich H, Heeren J, Virtanen KA, van Marken Lichtenbelt W, Pfeifer A. Chen Y, et al. Among authors: pfeifer a. Nat Commun. 2016 Apr 27;7:11420. doi: 10.1038/ncomms11420. Nat Commun. 2016. PMID: 27117818 Free PMC article.
Adenosine/A2B Receptor Signaling Ameliorates the Effects of Aging and Counteracts Obesity.
Gnad T, Navarro G, Lahesmaa M, Reverte-Salisa L, Copperi F, Cordomi A, Naumann J, Hochhäuser A, Haufs-Brusberg S, Wenzel D, Suhr F, Jespersen NZ, Scheele C, Tsvilovskyy V, Brinkmann C, Rittweger J, Dani C, Kranz M, Deuther-Conrad W, Eltzschig HK, Niemi T, Taittonen M, Brust P, Nuutila P, Pardo L, Fleischmann BK, Blüher M, Franco R, Bloch W, Virtanen KA, Pfeifer A. Gnad T, et al. Among authors: pfeifer a. Cell Metab. 2020 Jul 7;32(1):56-70.e7. doi: 10.1016/j.cmet.2020.06.006. Epub 2020 Jun 25. Cell Metab. 2020. PMID: 32589947 Free PMC article.
Apoptotic brown adipocytes enhance energy expenditure via extracellular inosine.
Niemann B, Haufs-Brusberg S, Puetz L, Feickert M, Jaeckstein MY, Hoffmann A, Zurkovic J, Heine M, Trautmann EM, Müller CE, Tönjes A, Schlein C, Jafari A, Eltzschig HK, Gnad T, Blüher M, Krahmer N, Kovacs P, Heeren J, Pfeifer A. Niemann B, et al. Among authors: pfeifer a. Nature. 2022 Sep;609(7926):361-368. doi: 10.1038/s41586-022-05041-0. Epub 2022 Jul 5. Nature. 2022. PMID: 35790189 Free PMC article.
Engraftment of connexin 43-expressing cells prevents post-infarct arrhythmia.
Roell W, Lewalter T, Sasse P, Tallini YN, Choi BR, Breitbach M, Doran R, Becher UM, Hwang SM, Bostani T, von Maltzahn J, Hofmann A, Reining S, Eiberger B, Gabris B, Pfeifer A, Welz A, Willecke K, Salama G, Schrickel JW, Kotlikoff MI, Fleischmann BK. Roell W, et al. Among authors: pfeifer a. Nature. 2007 Dec 6;450(7171):819-24. doi: 10.1038/nature06321. Nature. 2007. PMID: 18064002
425 results