Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

Search Results

425 results

Filters applied: . Clear all
Results are displayed in a computed author sort order. The Results By Year timeline is not available.
Page 1
Discovery and characterization of novel indole and 7-azaindole derivatives as inhibitors of β-amyloid-42 aggregation for the treatment of Alzheimer's disease.
Sreenivasachary N, Kroth H, Benderitter P, Hamel A, Varisco Y, Hickman DT, Froestl W, Pfeifer A, Muhs A. Sreenivasachary N, et al. Among authors: pfeifer a. Bioorg Med Chem Lett. 2017 Mar 15;27(6):1405-1411. doi: 10.1016/j.bmcl.2017.02.001. Epub 2017 Feb 4. Bioorg Med Chem Lett. 2017. PMID: 28216401
Discovery and structure activity relationship of small molecule inhibitors of toxic β-amyloid-42 fibril formation.
Kroth H, Ansaloni A, Varisco Y, Jan A, Sreenivasachary N, Rezaei-Ghaleh N, Giriens V, Lohmann S, López-Deber MP, Adolfsson O, Pihlgren M, Paganetti P, Froestl W, Nagel-Steger L, Willbold D, Schrader T, Zweckstetter M, Pfeifer A, Lashuel HA, Muhs A. Kroth H, et al. Among authors: pfeifer a. J Biol Chem. 2012 Oct 5;287(41):34786-800. doi: 10.1074/jbc.M112.357665. Epub 2012 Aug 13. J Biol Chem. 2012. PMID: 22891248 Free PMC article.
Discovery of 2-(4-(2-fluoroethoxy)piperidin-1-yl)-9-methyl-9H-pyrrolo[2,3-b:4,5-c']dipyridine ([18F]PI-2014) as PET tracer for the detection of pathological aggregated tau in Alzheimer's disease and other tauopathies.
Gabellieri E, Capotosti F, Molette J, Sreenivasachary N, Mueller A, Berndt M, Schieferstein H, Juergens T, Varisco Y, Oden F, Schmitt-Willich H, Hickman D, Dinkelborg L, Stephens A, Pfeifer A, Kroth H. Gabellieri E, et al. Among authors: pfeifer a. Eur J Med Chem. 2020 Oct 15;204:112615. doi: 10.1016/j.ejmech.2020.112615. Epub 2020 Jul 15. Eur J Med Chem. 2020. PMID: 32771872
PI-2620 Lead Optimization Highlights the Importance of Off-Target Assays to Develop a PET Tracer for the Detection of Pathological Aggregated Tau in Alzheimer's Disease and Other Tauopathies.
Kroth H, Oden F, Molette J, Schieferstein H, Gabellieri E, Mueller A, Berndt M, Sreenivasachary N, Serra AM, Capotosti F, Schmitt-Willich H, Hickman D, Pfeifer A, Dinkelborg L, Stephens A. Kroth H, et al. Among authors: pfeifer a. J Med Chem. 2021 Sep 9;64(17):12808-12830. doi: 10.1021/acs.jmedchem.1c00861. Epub 2021 Aug 29. J Med Chem. 2021. PMID: 34455780
Sequence-independent control of peptide conformation in liposomal vaccines for targeting protein misfolding diseases.
Hickman DT, López-Deber MP, Ndao DM, Silva AB, Nand D, Pihlgren M, Giriens V, Madani R, St-Pierre A, Karastaneva H, Nagel-Steger L, Willbold D, Riesner D, Nicolau C, Baldus M, Pfeifer A, Muhs A. Hickman DT, et al. Among authors: pfeifer a. J Biol Chem. 2011 Apr 22;286(16):13966-76. doi: 10.1074/jbc.M110.186338. Epub 2011 Feb 22. J Biol Chem. 2011. PMID: 21343310 Free PMC article.
An effector-reduced anti-β-amyloid (Aβ) antibody with unique aβ binding properties promotes neuroprotection and glial engulfment of Aβ.
Adolfsson O, Pihlgren M, Toni N, Varisco Y, Buccarello AL, Antoniello K, Lohmann S, Piorkowska K, Gafner V, Atwal JK, Maloney J, Chen M, Gogineni A, Weimer RM, Mortensen DL, Friesenhahn M, Ho C, Paul R, Pfeifer A, Muhs A, Watts RJ. Adolfsson O, et al. Among authors: pfeifer a. J Neurosci. 2012 Jul 11;32(28):9677-89. doi: 10.1523/JNEUROSCI.4742-11.2012. J Neurosci. 2012. PMID: 22787053 Free PMC article. Clinical Trial.
425 results