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Page 1
Microbes and asthma: Opportunities for intervention.
Smits HH, Hiemstra PS, Prazeres da Costa C, Ege M, Edwards M, Garn H, Howarth PH, Jartti T, de Jong EC, Maizels RM, Marsland BJ, McSorley HJ, Müller A, Pfefferle PI, Savelkoul H, Schwarze J, Unger WW, von Mutius E, Yazdanbakhsh M, Taube C. Smits HH, et al. Among authors: pfefferle pi. J Allergy Clin Immunol. 2016 Mar;137(3):690-7. doi: 10.1016/j.jaci.2016.01.004. J Allergy Clin Immunol. 2016. PMID: 26947981 Review.
Maturation of the gut microbiome during the first year of life contributes to the protective farm effect on childhood asthma.
Depner M, Taft DH, Kirjavainen PV, Kalanetra KM, Karvonen AM, Peschel S, Schmausser-Hechfellner E, Roduit C, Frei R, Lauener R, Divaret-Chauveau A, Dalphin JC, Riedler J, Roponen M, Kabesch M, Renz H, Pekkanen J, Farquharson FM, Louis P, Mills DA, von Mutius E; PASTURE study group; Ege MJ. Depner M, et al. Nat Med. 2020 Nov;26(11):1766-1775. doi: 10.1038/s41591-020-1095-x. Epub 2020 Nov 2. Nat Med. 2020. PMID: 33139948
Maternal TLR signaling is required for prenatal asthma protection by the nonpathogenic microbe Acinetobacter lwoffii F78.
Conrad ML, Ferstl R, Teich R, Brand S, Blümer N, Yildirim AO, Patrascan CC, Hanuszkiewicz A, Akira S, Wagner H, Holst O, von Mutius E, Pfefferle PI, Kirschning CJ, Garn H, Renz H. Conrad ML, et al. Among authors: pfefferle pi. J Exp Med. 2009 Dec 21;206(13):2869-77. doi: 10.1084/jem.20090845. Epub 2009 Dec 7. J Exp Med. 2009. PMID: 19995952 Free PMC article.
Epigenetic regulation in murine offspring as a novel mechanism for transmaternal asthma protection induced by microbes.
Brand S, Teich R, Dicke T, Harb H, Yildirim AÖ, Tost J, Schneider-Stock R, Waterland RA, Bauer UM, von Mutius E, Garn H, Pfefferle PI, Renz H. Brand S, et al. Among authors: pfefferle pi. J Allergy Clin Immunol. 2011 Sep;128(3):618-25.e1-7. doi: 10.1016/j.jaci.2011.04.035. Epub 2011 Jun 15. J Allergy Clin Immunol. 2011. PMID: 21680015
Clinical and epidemiologic phenotypes of childhood asthma.
Depner M, Fuchs O, Genuneit J, Karvonen AM, Hyvärinen A, Kaulek V, Roduit C, Weber J, Schaub B, Lauener R, Kabesch M, Pfefferle PI, Frey U, Pekkanen J, Dalphin JC, Riedler J, Braun-Fahrländer C, von Mutius E, Ege MJ; PASTURE Study Group. Depner M, et al. Among authors: pfefferle pi. Am J Respir Crit Care Med. 2014 Jan 15;189(2):129-38. doi: 10.1164/rccm.201307-1198OC. Am J Respir Crit Care Med. 2014. PMID: 24283801
Farm-like indoor microbiota in non-farm homes protects children from asthma development.
Kirjavainen PV, Karvonen AM, Adams RI, Täubel M, Roponen M, Tuoresmäki P, Loss G, Jayaprakash B, Depner M, Ege MJ, Renz H, Pfefferle PI, Schaub B, Lauener R, Hyvärinen A, Knight R, Heederik DJJ, von Mutius E, Pekkanen J. Kirjavainen PV, et al. Among authors: pfefferle pi. Nat Med. 2019 Jul;25(7):1089-1095. doi: 10.1038/s41591-019-0469-4. Epub 2019 Jun 17. Nat Med. 2019. PMID: 31209334
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