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Target modulation by a kinase inhibitor engineered to induce a tandem blockade of the epidermal growth factor receptor (EGFR) and c-Src: the concept of type III combi-targeting.
PLoS One. 2015 Feb 6;10(2):e0117215. doi: 10.1371/journal.pone.0117215. eCollection 2015.
PLoS One. 2015.
PMID: 25658745
Free PMC article.
Positional isomerization of a non-cleavable combi-molecule dramatically altered tumor cell response profile.
Huang Y, Rachid Z, Peyrard L, Senhaji Mouhri Z, Williams C, Jean-Claude BJ.
Huang Y, et al. Among authors: peyrard l.
Chem Biol Drug Des. 2015 Feb;85(2):153-62. doi: 10.1111/cbdd.12402. Epub 2014 Sep 25.
Chem Biol Drug Des. 2015.
PMID: 25092264
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Quantitative Analysis of the Potency of Equimolar Two-Drug Combinations and Combi-Molecules Involving Kinase Inhibitors In Vitro: The Concept of Balanced Targeting.
Rao S, Thibault B, Peyrard L, Larroque-Lombard AL, Rupp M, Thauvin C, Jean-Claude BJ.
Rao S, et al. Among authors: peyrard l.
Int J Mol Sci. 2021 Sep 3;22(17):9569. doi: 10.3390/ijms22179569.
Int J Mol Sci. 2021.
PMID: 34502481
Free PMC article.
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Subcellular distribution and mechanism of action of AL906, a novel and potent EGFR inhibitor rationally designed to be green fluorescent.
Golabi N, Larroque AL, Peyrard L, Williams C, Jean-Claude BJ.
Golabi N, et al. Among authors: peyrard l.
Invest New Drugs. 2021 Feb;39(1):240-250. doi: 10.1007/s10637-020-00958-7. Epub 2020 Jul 9.
Invest New Drugs. 2021.
PMID: 32648119
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Development of functionalized cyclotriveratrylene analogues: introduction of withdrawing and π-conjugated groups.
Peyrard L, Dumartin ML, Chierici S, Pinet S, Jonusauskas G, Meyrand P, Gosse I.
Peyrard L, et al.
J Org Chem. 2012 Aug 17;77(16):7023-7. doi: 10.1021/jo301183b. Epub 2012 Aug 9.
J Org Chem. 2012.
PMID: 22845697
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C3-triiodocyclotriveratrylene as a key intermediate to fluorescent probes: application to selective choline recognition.
Peyrard L, Chierici S, Pinet S, Batat P, Jonusauskas G, Pinaud N, Meyrand P, Gosse I.
Peyrard L, et al.
Org Biomol Chem. 2011 Dec 21;9(24):8489-94. doi: 10.1039/c1ob06231j. Epub 2011 Oct 31.
Org Biomol Chem. 2011.
PMID: 22038183
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