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Lessons from Two Design-Build-Test-Learn Cycles of Dodecanol Production in Escherichia coli Aided by Machine Learning.
Opgenorth P, Costello Z, Okada T, Goyal G, Chen Y, Gin J, Benites V, de Raad M, Northen TR, Deng K, Deutsch S, Baidoo EEK, Petzold CJ, Hillson NJ, Garcia Martin H, Beller HR. Opgenorth P, et al. Among authors: petzold cj. ACS Synth Biol. 2019 Jun 21;8(6):1337-1351. doi: 10.1021/acssynbio.9b00020. Epub 2019 May 24. ACS Synth Biol. 2019. PMID: 31072100 Free article.
Expanding Extender Substrate Selection for Unnatural Polyketide Biosynthesis by Acyltransferase Domain Exchange within a Modular Polyketide Synthase.
Englund E, Schmidt M, Nava AA, Lechner A, Deng K, Jocic R, Lin Y, Roberts J, Benites VT, Kakumanu R, Gin JW, Chen Y, Liu Y, Petzold CJ, Baidoo EEK, Northen TR, Adams PD, Katz L, Yuzawa S, Keasling JD. Englund E, et al. Among authors: petzold cj. J Am Chem Soc. 2023 Apr 26;145(16):8822-8832. doi: 10.1021/jacs.2c11027. Epub 2023 Apr 14. J Am Chem Soc. 2023. PMID: 37057992 Free PMC article.
Complete integration of carbene-transfer chemistry into biosynthesis.
Huang J, Quest A, Cruz-Morales P, Deng K, Pereira JH, Van Cura D, Kakumanu R, Baidoo EEK, Dan Q, Chen Y, Petzold CJ, Northen TR, Adams PD, Clark DS, Balskus EP, Hartwig JF, Mukhopadhyay A, Keasling JD. Huang J, et al. Among authors: petzold cj. Nature. 2023 May;617(7960):403-408. doi: 10.1038/s41586-023-06027-2. Epub 2023 May 3. Nature. 2023. PMID: 37138074
Discovery of enzymes for toluene synthesis from anoxic microbial communities.
Beller HR, Rodrigues AV, Zargar K, Wu YW, Saini AK, Saville RM, Pereira JH, Adams PD, Tringe SG, Petzold CJ, Keasling JD. Beller HR, et al. Among authors: petzold cj. Nat Chem Biol. 2018 May;14(5):451-457. doi: 10.1038/s41589-018-0017-4. Epub 2018 Mar 19. Nat Chem Biol. 2018. PMID: 29556105
Targeted proteomics for metabolic pathway optimization.
Batth TS, Keasling JD, Petzold CJ. Batth TS, et al. Among authors: petzold cj. Methods Mol Biol. 2012;944:237-49. doi: 10.1007/978-1-62703-122-6_17. Methods Mol Biol. 2012. PMID: 23065621
154 results