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Machine learning and data mining frameworks for predicting drug response in cancer: An overview and a novel in silico screening process based on association rule mining.
Vougas K, Sakellaropoulos T, Kotsinas A, Foukas GP, Ntargaras A, Koinis F, Polyzos A, Myrianthopoulos V, Zhou H, Narang S, Georgoulias V, Alexopoulos L, Aifantis I, Townsend PA, Sfikakis P, Fitzgerald R, Thanos D, Bartek J, Petty R, Tsirigos A, Gorgoulis VG. Vougas K, et al. Among authors: petty r. Pharmacol Ther. 2019 Nov;203:107395. doi: 10.1016/j.pharmthera.2019.107395. Epub 2019 Jul 30. Pharmacol Ther. 2019. PMID: 31374225 Review.
A Deep Learning Framework for Predicting Response to Therapy in Cancer.
Sakellaropoulos T, Vougas K, Narang S, Koinis F, Kotsinas A, Polyzos A, Moss TJ, Piha-Paul S, Zhou H, Kardala E, Damianidou E, Alexopoulos LG, Aifantis I, Townsend PA, Panayiotidis MI, Sfikakis P, Bartek J, Fitzgerald RC, Thanos D, Mills Shaw KR, Petty R, Tsirigos A, Gorgoulis VG. Sakellaropoulos T, et al. Among authors: petty r. Cell Rep. 2019 Dec 10;29(11):3367-3373.e4. doi: 10.1016/j.celrep.2019.11.017. Cell Rep. 2019. PMID: 31825821 Free article.
Discovery of a new generation of angiotensin receptor blocking drugs: Receptor mechanisms and in silico binding to enzymes relevant to SARS-CoV-2.
Ridgway H, Moore GJ, Mavromoustakos T, Tsiodras S, Ligielli I, Kelaidonis K, Chasapis CT, Gadanec LK, Zulli A, Apostolopoulos V, Petty R, Karakasiliotis I, Gorgoulis VG, Matsoukas JM. Ridgway H, et al. Among authors: petty r. Comput Struct Biotechnol J. 2022;20:2091-2111. doi: 10.1016/j.csbj.2022.04.010. Epub 2022 Apr 9. Comput Struct Biotechnol J. 2022. PMID: 35432786 Free PMC article.
Rearrangement processes and structural variations show evidence of selection in oesophageal adenocarcinomas.
Ng AWT, Contino G, Killcoyne S, Devonshire G, Hsu R, Abbas S, Su J, Redmond AM, Weaver JMJ, Eldridge MD, Tavaré S; Oesophageal Cancer Clinical and Molecular Stratification (OCCAMS) Consortium; Edwards PAW, Fitzgerald RC. Ng AWT, et al. Commun Biol. 2022 Apr 8;5(1):335. doi: 10.1038/s42003-022-03238-7. Commun Biol. 2022. PMID: 35396535 Free PMC article.
ELEVATE - evaluating Temozolomide and Nivolumab in patients with advanced unresectable previously treated oesophagogastric adenocarcinoma with MGMT methylation: study protocol for a single arm phase II trial.
Smyth E, Cozens K, Griffiths D, Clark KL, Ewings S, Petty R, Underwood T, Fitzgerald RC, Tanner J, Giger O, Anand S, Griffiths G. Smyth E, et al. Among authors: petty r. BMC Cancer. 2022 Sep 1;22(1):946. doi: 10.1186/s12885-022-09891-9. BMC Cancer. 2022. PMID: 36050653 Free PMC article.
582 results