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Intranasal challenge with B. pertussis leads to more severe disease manifestations in mice than aerosol challenge.
Weaver KL, Bitzer GJ, Wolf MA, Pyles GM, DeJong MA, Dublin SR, Huckaby AB, Gutierrez MP, Hall JM, Wong TY, Warden M, Petty JE, Witt WT, Cunningham C, Sen-Kilic E, Damron FH, Barbier M. Weaver KL, et al. Among authors: petty je. PLoS One. 2023 Nov 2;18(11):e0286925. doi: 10.1371/journal.pone.0286925. eCollection 2023. PLoS One. 2023. PMID: 37917623 Free PMC article.
BECC438b TLR4 agonist supports unique immune response profiles from nasal and muscular DTaP pertussis vaccines in murine challenge models.
DeJong MA, Wolf MA, Bitzer GJ, Hall JM, Fitzgerald NA, Pyles GM, Huckaby AB, Petty JE, Lee K, Barbier M, Bevere JR, Ernst RK, Damron FH. DeJong MA, et al. Among authors: petty je. Infect Immun. 2024 Mar 12;92(3):e0022323. doi: 10.1128/iai.00223-23. Epub 2024 Feb 7. Infect Immun. 2024. PMID: 38323817 Free PMC article.