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Case report: Preclinical efficacy of NEDD8 and proteasome inhibitors in patient-derived models of signet ring high-grade mucinous colorectal cancer from a Lynch syndrome patient.
Torchiaro E, Petti C, Arena S, Sassi F, Migliardi G, Mellano A, Porporato R, Basiricò M, Gammaitoni L, Berrino E, Montone M, Corti G, Crisafulli G, Marchiò C, Bardelli A, Medico E. Torchiaro E, et al. Among authors: petti c. Front Oncol. 2023 Feb 2;13:1130852. doi: 10.3389/fonc.2023.1130852. eCollection 2023. Front Oncol. 2023. PMID: 36816936 Free PMC article.
Efficacy of NEDD8 Pathway Inhibition in Preclinical Models of Poorly Differentiated, Clinically Aggressive Colorectal Cancer.
Picco G, Petti C, Sassi F, Grillone K, Migliardi G, Rossi T, Isella C, Di Nicolantonio F, Sarotto I, Sapino A, Bardelli A, Trusolino L, Bertotti A, Medico E. Picco G, et al. Among authors: petti c. J Natl Cancer Inst. 2016 Oct 22;109(2):djw209. doi: 10.1093/jnci/djw209. Print 2017 Feb. J Natl Cancer Inst. 2016. PMID: 27771609 Free article.
Patient-derived xenografts (PDXs) as model systems for human cancer.
Invrea F, Rovito R, Torchiaro E, Petti C, Isella C, Medico E. Invrea F, et al. Among authors: petti c. Curr Opin Biotechnol. 2020 Jun;63:151-156. doi: 10.1016/j.copbio.2020.01.003. Epub 2020 Feb 18. Curr Opin Biotechnol. 2020. PMID: 32070860 Free article. Review.
Synthetic Lethality Screening Highlights Colorectal Cancer Vulnerability to Concomitant Blockade of NEDD8 and EGFR Pathways.
Invrea F, Punzi S, Petti C, Minelli R, Peoples MD, Bristow CA, Vurchio V, Corrado A, Bragoni A, Marchiò C, Bertotti A, Trusolino L, Bardelli A, Isella C, Carugo A, Draetta GF, Medico E. Invrea F, et al. Among authors: petti c. Cancers (Basel). 2021 Jul 28;13(15):3805. doi: 10.3390/cancers13153805. Cancers (Basel). 2021. PMID: 34359705 Free PMC article.
A molecularly annotated platform of patient-derived xenografts ("xenopatients") identifies HER2 as an effective therapeutic target in cetuximab-resistant colorectal cancer.
Bertotti A, Migliardi G, Galimi F, Sassi F, Torti D, Isella C, Corà D, Di Nicolantonio F, Buscarino M, Petti C, Ribero D, Russolillo N, Muratore A, Massucco P, Pisacane A, Molinaro L, Valtorta E, Sartore-Bianchi A, Risio M, Capussotti L, Gambacorta M, Siena S, Medico E, Sapino A, Marsoni S, Comoglio PM, Bardelli A, Trusolino L. Bertotti A, et al. Among authors: petti c. Cancer Discov. 2011 Nov;1(6):508-23. doi: 10.1158/2159-8290.CD-11-0109. Epub 2011 Sep 2. Cancer Discov. 2011. PMID: 22586653 Free article.
Selective analysis of cancer-cell intrinsic transcriptional traits defines novel clinically relevant subtypes of colorectal cancer.
Isella C, Brundu F, Bellomo SE, Galimi F, Zanella E, Porporato R, Petti C, Fiori A, Orzan F, Senetta R, Boccaccio C, Ficarra E, Marchionni L, Trusolino L, Medico E, Bertotti A. Isella C, et al. Among authors: petti c. Nat Commun. 2017 May 31;8:15107. doi: 10.1038/ncomms15107. Nat Commun. 2017. PMID: 28561063 Free PMC article.
Stromal contribution to the colorectal cancer transcriptome.
Isella C, Terrasi A, Bellomo SE, Petti C, Galatola G, Muratore A, Mellano A, Senetta R, Cassenti A, Sonetto C, Inghirami G, Trusolino L, Fekete Z, De Ridder M, Cassoni P, Storme G, Bertotti A, Medico E. Isella C, et al. Among authors: petti c. Nat Genet. 2015 Apr;47(4):312-9. doi: 10.1038/ng.3224. Epub 2015 Feb 23. Nat Genet. 2015. PMID: 25706627 Free article.
128 results