Petrov AM - Search Results

1

CYP46A1-dependent and independent effects of efavirenz treatment.

Mast N, El-Darzi N, Petrov AM, Li Y, Pikuleva IA. Mast N, et al. Among authors: petrov am. Brain Commun. 2020 Oct 29;2(2):fcaa180. doi: 10.1093/braincomms/fcaa180. eCollection 2020. Brain Commun. 2020. PMID: 33305262 Free PMC article.

2

2-Hydroxypropyl-β-cyclodextrin reduces retinal cholesterol in wild-type and Cyp27a1^-/- Cyp46a1^-/- mice with deficiency in the oxysterol production.

El-Darzi N, Mast N, Petrov AM, Pikuleva IA. El-Darzi N, et al. Among authors: petrov am. Br J Pharmacol. 2021 Aug;178(16):3220-3234. doi: 10.1111/bph.15209. Epub 2020 Aug 13. Br J Pharmacol. 2021. PMID: 32698250 Free PMC article.

3

Brain Acetyl-CoA Production and Phosphorylation of Cytoskeletal Proteins Are Targets of CYP46A1 Activity Modulation and Altered Sterol Flux.

Mast N, Petrov AM, Prendergast E, Bederman I, Pikuleva IA. Mast N, et al. Among authors: petrov am. Neurotherapeutics. 2021 Jul;18(3):2040-2060. doi: 10.1007/s13311-021-01079-6. Epub 2021 Jul 7. Neurotherapeutics. 2021. PMID: 34235635 Free PMC article.

4

Cholesterol 24-Hydroxylation by CYP46A1: Benefits of Modulation for Brain Diseases.

Petrov AM, Pikuleva IA. Petrov AM, et al. Neurotherapeutics. 2019 Jul;16(3):635-648. doi: 10.1007/s13311-019-00731-6. Neurotherapeutics. 2019. PMID: 31001737 Free PMC article. Review.

5

CYP46A1 Activation by Efavirenz Leads to Behavioral Improvement without Significant Changes in Amyloid Plaque Load in the Brain of 5XFAD Mice.

Petrov AM, Lam M, Mast N, Moon J, Li Y, Maxfield E, Pikuleva IA. Petrov AM, et al. Neurotherapeutics. 2019 Jul;16(3):710-724. doi: 10.1007/s13311-019-00737-0. Neurotherapeutics. 2019. PMID: 31062296 Free PMC article.

6

The key genes, phosphoproteins, processes, and pathways affected by efavirenz-activated CYP46A1 in the amyloid-decreasing paradigm of efavirenz treatment.

Petrov AM, Mast N, Li Y, Pikuleva IA. Petrov AM, et al. FASEB J. 2019 Aug;33(8):8782-8798. doi: 10.1096/fj.201900092R. Epub 2019 May 7. FASEB J. 2019. PMID: 31063705 Free PMC article.

7

Brain sterol flux mediated by cytochrome P450 46A1 affects membrane properties and membrane-dependent processes.

Petrov AM, Mast N, Li Y, Denker J, Pikuleva IA. Petrov AM, et al. Brain Commun. 2020;2(1):fcaa043. doi: 10.1093/braincomms/fcaa043. Epub 2020 Apr 11. Brain Commun. 2020. PMID: 32661514 Free PMC article.

8

Mechanisms that minimize retinal impact of apolipoprotein E absence.

Saadane A, Petrov A, Mast N, El-Darzi N, Dao T, Alnemri A, Song Y, Dunaief JL, Pikuleva IA. Saadane A, et al. J Lipid Res. 2018 Dec;59(12):2368-2382. doi: 10.1194/jlr.M090043. Epub 2018 Oct 17. J Lipid Res. 2018. PMID: 30333155 Free PMC article.

9

The Interplay between Retinal Pathways of Cholesterol Output and Its Effects on Mouse Retina.

Petrov AM, Astafev AA, Mast N, Saadane A, El-Darzi N, Pikuleva IA. Petrov AM, et al. Biomolecules. 2019 Dec 12;9(12):867. doi: 10.3390/biom9120867. Biomolecules. 2019. PMID: 31842366 Free PMC article.

10

Studies of ApoD^-/- and ApoD^-/-ApoE^-/- mice uncover the APOD significance for retinal metabolism, function, and status of chorioretinal blood vessels.

El-Darzi N, Mast N, Petrov AM, Dao T, Astafev AA, Saadane A, Prendergast E, Schwarz E, Bederman I, Pikuleva IA. El-Darzi N, et al. Among authors: petrov am. Cell Mol Life Sci. 2021 Feb;78(3):963-983. doi: 10.1007/s00018-020-03546-3. Epub 2020 May 21. Cell Mol Life Sci. 2021. PMID: 32440710 Free PMC article.

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