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Sensitivity of different resistant tumour cell lines to the two novel compounds (2Z,4E)-2-methylsulfanyl-5-(1-naphthyl)-4-nitro-2,4-pentadienoate and (1E,3E)-1,4-bis(2-naphthyl)-2,3-dinitro-1,3-butadiene.
Viale M, Petrillo G, Maccagno M, Castagnola P, Aiello C, Cordazzo C, Mariggiò MA, Jadhav SA, Bianchi L, Leto G, Rizzato E, Poggi A, Spinelli D. Viale M, et al. Among authors: petrillo g. Eur J Pharmacol. 2008 Jun 24;588(1):47-51. doi: 10.1016/j.ejphar.2008.04.020. Epub 2008 Apr 12. Eur J Pharmacol. 2008. PMID: 18495109
Inhibition of cell proliferation, cytotoxicity and induction of apoptosis of 1,4-bis(1-naphthyl)-2,3-dinitro-1,3-butadiene in gastrointestinal tumour cell lines and preliminary evaluation of its toxicity in vivo.
Dell'Erba C, Chiavarina B, Fenoglio C, Petrillo G, Cordazzo C, Boncompagni E, Spinelli D, Ognio E, Aiello C, Mariggiò MA, Viale M. Dell'Erba C, et al. Among authors: petrillo g. Pharmacol Res. 2005 Sep;52(3):271-82. doi: 10.1016/j.phrs.2005.03.011. Pharmacol Res. 2005. PMID: 15921920
Synthesis, in vitro activity and in vivo toxicity of the new 2,3-dinitrobutadiene derivative (1E,3E)-1,4-bis(2-naphthyl)-2,3-dinitro-1,3-butadiene.
Viale M, Petrillo G, Aiello C, Fenoglio C, Cordazzo C, Mariggiò MA, Cassano A, Prevosto C, Ognio E, Maccagno M, Bianchi L, Vaccarone R, Rizzato E, Spinelli D. Viale M, et al. Among authors: petrillo g. Pharmacol Res. 2007 Oct;56(4):318-28. doi: 10.1016/j.phrs.2007.07.009. Epub 2007 Aug 3. Pharmacol Res. 2007. PMID: 17827031
Design, synthesis, and in vitro evaluation of new naphthylnitrobutadienes with potential antiproliferative activity: toward a structure/activity correlation.
Petrillo G, Mariggiò MA, Aiello C, Cordazzo C, Fenoglio C, Morganti S, Croce M, Rizzato E, Spinelli D, Maccagno M, Bianchi L, Prevosto C, Tavani C, Viale M. Petrillo G, et al. Bioorg Med Chem. 2008 Jan 1;16(1):240-7. doi: 10.1016/j.bmc.2007.09.042. Epub 2007 Sep 26. Bioorg Med Chem. 2008. PMID: 17936630
284 results