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Circulating extracellular vesicles from individuals at high-risk of lung cancer induce pro-tumorigenic conversion of stromal cells through transfer of miR-126 and miR-320.
Pontis F, Roz L, Mensah M, Segale M, Moro M, Bertolini G, Petraroia I, Centonze G, Ferretti AM, Suatoni P, Pastorino U, Fortunato O, Sozzi G. Pontis F, et al. Among authors: petraroia i. J Exp Clin Cancer Res. 2021 Jul 21;40(1):237. doi: 10.1186/s13046-021-02040-3. J Exp Clin Cancer Res. 2021. PMID: 34289890 Free PMC article.
Cotargeting of miR-126-3p and miR-221-3p inhibits PIK3R2 and PTEN, reducing lung cancer growth and metastasis by blocking AKT and CXCR4 signalling.
Di Paolo D, Pontis F, Moro M, Centonze G, Bertolini G, Milione M, Mensah M, Segale M, Petraroia I, Borzi C, Suatoni P, Brignole C, Perri P, Ponzoni M, Pastorino U, Sozzi G, Fortunato O. Di Paolo D, et al. Among authors: petraroia i. Mol Oncol. 2021 Nov;15(11):2969-2988. doi: 10.1002/1878-0261.13036. Epub 2021 Jul 21. Mol Oncol. 2021. PMID: 34107168 Free PMC article.
Circulating CD81-expressing extracellular vesicles as biomarkers of response for immune-checkpoint inhibitors in advanced NSCLC.
Signorelli D, Ghidotti P, Proto C, Brambilla M, De Toma A, Ferrara R, Galli G, Ganzinelli M, Lo Russo G, Prelaj A, Occhipinti M, Viscardi G, Capizzuto V, Pontis F, Petraroia I, Ferretti AM, Colombo MP, Torri V, Sozzi G, Garassino MC, Jachetti E, Fortunato O. Signorelli D, et al. Among authors: petraroia i. Front Immunol. 2022 Sep 20;13:987639. doi: 10.3389/fimmu.2022.987639. eCollection 2022. Front Immunol. 2022. PMID: 36203609 Free PMC article.
BMP7 promotes cardiomyocyte regeneration in zebrafish and adult mice.
Bongiovanni C, Bueno-Levy H, Posadas Pena D, Del Bono I, Miano C, Boriati S, Da Pra S, Sacchi F, Redaelli S, Bergen M, Romaniello D, Pontis F, Tassinari R, Kellerer L, Petraroia I, Mazzeschi M, Lauriola M, Ventura C, Heermann S, Weidinger G, Tzahor E, D'Uva G. Bongiovanni C, et al. Among authors: petraroia i. Cell Rep. 2024 Apr 27;43(5):114162. doi: 10.1016/j.celrep.2024.114162. Online ahead of print. Cell Rep. 2024. PMID: 38678558 Free article.
MiR-223 Exclusively Impairs In Vitro Tumor Growth through IGF1R Modulation in Rhabdomyosarcoma of Adolescents and Young Adults.
Casanova M, Pontis F, Ghidotti P, Petraroia I, Venturini LV, Bergamaschi L, Chiaravalli S, De Cecco L, Massimino M, Sozzi G, Ferrari A, Fortunato O, Gasparini P. Casanova M, et al. Among authors: petraroia i. Int J Mol Sci. 2022 Nov 13;23(22):13989. doi: 10.3390/ijms232213989. Int J Mol Sci. 2022. PMID: 36430468 Free PMC article.