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Reactive astrocytes promote proteostasis in Huntington's disease through the JAK2-STAT3 pathway.
Abjean L, Ben Haim L, Riquelme-Perez M, Gipchtein P, Derbois C, Palomares MA, Petit F, Hérard AS, Gaillard MC, Guillermier M, Gaudin-Guérif M, Aurégan G, Sagar N, Héry C, Dufour N, Robil N, Kabani M, Melki R, De la Grange P, Bemelmans AP, Bonvento G, Deleuze JF, Hantraye P, Flament J, Bonnet E, Brohard S, Olaso R, Brouillet E, Carrillo-de Sauvage MA, Escartin C. Abjean L, et al. Among authors: petit f. Brain. 2023 Jan 5;146(1):149-166. doi: 10.1093/brain/awac068. Brain. 2023. PMID: 35298632
Normal aging modulates the neurotoxicity of mutant huntingtin.
Diguet E, Petit F, Escartin C, Cambon K, Bizat N, Dufour N, Hantraye P, Déglon N, Brouillet E. Diguet E, et al. Among authors: petit f. PLoS One. 2009;4(2):e4637. doi: 10.1371/journal.pone.0004637. Epub 2009 Feb 27. PLoS One. 2009. PMID: 19247483 Free PMC article.
Capucin does not modify the toxicity of a mutant Huntingtin fragment in vivo.
Galvan L, Lepejová N, Gaillard MC, Malgorn C, Guillermier M, Houitte D, Bonvento G, Petit F, Dufour N, Héry P, Gérard M, Elalouf JM, Déglon N, Brouillet E, de Chaldée M. Galvan L, et al. Among authors: petit f. Neurobiol Aging. 2012 Aug;33(8):1845.e5-6. doi: 10.1016/j.neurobiolaging.2012.01.009. Epub 2012 Feb 24. Neurobiol Aging. 2012. PMID: 22365050
A role of mitochondrial complex II defects in genetic models of Huntington's disease expressing N-terminal fragments of mutant huntingtin.
Damiano M, Diguet E, Malgorn C, D'Aurelio M, Galvan L, Petit F, Benhaim L, Guillermier M, Houitte D, Dufour N, Hantraye P, Canals JM, Alberch J, Delzescaux T, Déglon N, Beal MF, Brouillet E. Damiano M, et al. Among authors: petit f. Hum Mol Genet. 2013 Oct 1;22(19):3869-82. doi: 10.1093/hmg/ddt242. Epub 2013 May 29. Hum Mol Genet. 2013. PMID: 23720495 Free PMC article.
Impaired brain energy metabolism in the BACHD mouse model of Huntington's disease: critical role of astrocyte-neuron interactions.
Boussicault L, Hérard AS, Calingasan N, Petit F, Malgorn C, Merienne N, Jan C, Gaillard MC, Lerchundi R, Barros LF, Escartin C, Delzescaux T, Mariani J, Hantraye P, Beal MF, Brouillet E, Véga C, Bonvento G. Boussicault L, et al. Among authors: petit f. J Cereb Blood Flow Metab. 2014 Sep;34(9):1500-10. doi: 10.1038/jcbfm.2014.110. Epub 2014 Jun 18. J Cereb Blood Flow Metab. 2014. PMID: 24938402 Free PMC article.
Loss of the thyroid hormone-binding protein Crym renders striatal neurons more vulnerable to mutant huntingtin in Huntington's disease.
Francelle L, Galvan L, Gaillard MC, Guillermier M, Houitte D, Bonvento G, Petit F, Jan C, Dufour N, Hantraye P, Elalouf JM, De Chaldée M, Déglon N, Brouillet E. Francelle L, et al. Among authors: petit f. Hum Mol Genet. 2015 Mar 15;24(6):1563-73. doi: 10.1093/hmg/ddu571. Epub 2014 Nov 14. Hum Mol Genet. 2015. PMID: 25398949 Free PMC article.
499 results