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SorLA controls neurotrophic activity by sorting of GDNF and its receptors GFRα1 and RET.
Glerup S, Lume M, Olsen D, Nyengaard JR, Vaegter CB, Gustafsen C, Christensen EI, Kjolby M, Hay-Schmidt A, Bender D, Madsen P, Saarma M, Nykjaer A, Petersen CM. Glerup S, et al. Among authors: petersen cm. Cell Rep. 2013 Jan 31;3(1):186-99. doi: 10.1016/j.celrep.2012.12.011. Epub 2013 Jan 17. Cell Rep. 2013. PMID: 23333276 Free article.
Functional organization of the sortilin Vps10p domain.
Westergaard UB, Sørensen ES, Hermey G, Nielsen MS, Nykjaer A, Kirkegaard K, Jacobsen C, Gliemann J, Madsen P, Petersen CM. Westergaard UB, et al. Among authors: petersen cm. J Biol Chem. 2004 Nov 26;279(48):50221-9. doi: 10.1074/jbc.M408873200. Epub 2004 Sep 10. J Biol Chem. 2004. PMID: 15364913 Free article.
SorLA regulates the activity of lipoprotein lipase by intracellular trafficking.
Klinger SC, Glerup S, Raarup MK, Mari MC, Nyegaard M, Koster G, Prabakaran T, Nilsson SK, Kjaergaard MM, Bakke O, Nykjær A, Olivecrona G, Petersen CM, Nielsen MS. Klinger SC, et al. Among authors: petersen cm. J Cell Sci. 2011 Apr 1;124(Pt 7):1095-105. doi: 10.1242/jcs.072538. Epub 2011 Mar 8. J Cell Sci. 2011. PMID: 21385844 Free article.
Sortilin is essential for proNGF-induced neuronal cell death.
Nykjaer A, Lee R, Teng KK, Jansen P, Madsen P, Nielsen MS, Jacobsen C, Kliemannel M, Schwarz E, Willnow TE, Hempstead BL, Petersen CM. Nykjaer A, et al. Among authors: petersen cm. Nature. 2004 Feb 26;427(6977):843-8. doi: 10.1038/nature02319. Nature. 2004. PMID: 14985763
117 results