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Page 1
Discovery of IRAK4 Inhibitors BAY1834845 (Zabedosertib) and BAY1830839.
Bothe U, Günther J, Nubbemeyer R, Siebeneicher H, Ring S, Bömer U, Peters M, Rausch A, Denner K, Himmel H, Sutter A, Terebesi I, Lange M, Wengner AM, Guimond N, Thaler T, Platzek J, Eberspächer U, Schäfer M, Steuber H, Zollner TM, Steinmeyer A, Schmidt N. Bothe U, et al. Among authors: peters m. J Med Chem. 2024 Jan 25;67(2):1225-1242. doi: 10.1021/acs.jmedchem.3c01714. Epub 2024 Jan 16. J Med Chem. 2024. PMID: 38228402 Free PMC article.
Discovery and optimization of pyridyl-cycloalkyl-carboxylic acids as inhibitors of microsomal prostaglandin E synthase-1 for the treatment of endometriosis.
Koppitz M, Bräuer N, Ter Laak A, Irlbacher H, Rotgeri A, Coelho AM, Walter D, Steinmeyer A, Zollner TM, Peters M, Nagel J. Koppitz M, et al. Among authors: peters m. Bioorg Med Chem Lett. 2019 Sep 15;29(18):2700-2705. doi: 10.1016/j.bmcl.2019.07.007. Epub 2019 Jul 24. Bioorg Med Chem Lett. 2019. PMID: 31362919
Novel aldo-keto reductase 1C3 inhibitor affects androgen metabolism but not ovarian function in healthy women: a phase 1 study.
Gashaw I, Reif S, Wiesinger H, Kaiser A, Zollmann FS, Scheerans C, Grevel J, Piraino P, Seidel H, Peters M, Rottmann A, Rohde B, Arlt W, Hilpert J. Gashaw I, et al. Among authors: peters m. Eur J Endocrinol. 2023 Jul 10;188(7):578-591. doi: 10.1093/ejendo/lvad063. Eur J Endocrinol. 2023. PMID: 37306288 Free PMC article. Clinical Trial.
Exploring definitions and predictors of response to biologics for severe asthma.
Scelo G, Tran TN, Le TT, Faregås M, Dorscheid D, Busby J, Al-Ahmad M, Al-Lehebi R, Altraja A, Beastall A, Bergeron C, Bjermer L, Bjerrum AS, Cano-Rosales DJ, Canonica GW, Carter V, Charriot J, Christoff GC, Cosio BG, Denton E, Fernandez-Sanchez MJ, Fonseca JA, Gibson PG, Goh C, Heaney LG, Heffler E, Hew M, Iwanaga T, Katial R, Koh MS, Kuna P, Larenas-Linnemann D, Lehtimäki L, Mahboub B, Martin N, Matsumoto H, Menzies-Gow AN, Papadopoulos NG, Patel P, Perez-De-Llano L, Peters M, Pfeffer PE, Popov TA, Porsbjerg CM, Rhee CK, Sadatsafavi M, Taillé C, Torres-Duque CA, Tsai MJ, Ulrik CS, Upham JW, von Bülow A, Wang E, Wechsler ME, Price DB. Scelo G, et al. Among authors: peters m. J Allergy Clin Immunol Pract. 2024 May 18:S2213-2198(24)00530-0. doi: 10.1016/j.jaip.2024.05.016. Online ahead of print. J Allergy Clin Immunol Pract. 2024. PMID: 38768896
Enhanced CD95 and interleukin 18 signalling accompany T cell receptor Vβ21.3+ activation in multi-inflammatory syndrome in children.
Zhang Z, Kean IRL, Dratva LM, Clark JA, Syrimi E, Khan N, Daubney E, White D, O'Neill L, Chisholm C, Payne C, Benkenstein S, Kupiec K, Galassini R, Wright V, Winmill H, Robbins C, Brown K, Ramnarayan P, Scholefield B, Peters M, Klein N, Montgomery H, Meyer KB, Teichmann SA, Bryant C, Taylor G, Pathan N. Zhang Z, et al. Among authors: peters m. Nat Commun. 2024 May 18;15(1):4227. doi: 10.1038/s41467-024-48699-y. Nat Commun. 2024. PMID: 38762592 Free PMC article.
Mapping recurrent mosaic copy number variation in human neurons.
Sun C, Kathuria K, Emery SB, Kim B, Burbulis IE, Shin JH; Brain Somatic Mosaicism Network; Weinberger DR, Moran JV, Kidd JM, Mills RE, McConnell MJ. Sun C, et al. Nat Commun. 2024 May 17;15(1):4220. doi: 10.1038/s41467-024-48392-0. Nat Commun. 2024. PMID: 38760338 Free PMC article.
Hydropneumopericardium Due to a Traumatic Esophageal-Pericardial Fistula.
Sagheer U, Bhandari S, Umer M, Peters M, Shotwell M, Liu N, Royer A, Mylarapu A, Kalra DK. Sagheer U, et al. Among authors: peters m. JACC Case Rep. 2024 May 6;29(12):102357. doi: 10.1016/j.jaccas.2024.102357. eCollection 2024 Jun 19. JACC Case Rep. 2024. PMID: 38751806 Free PMC article.
A common polymorphism in the Intelectin-1 gene influences mucus plugging in severe asthma.
Everman JL, Sajuthi SP, Liegeois MA, Jackson ND, Collet EH, Peters MC, Chioccioli M, Moore CM, Patel BB, Dyjack N, Powell R, Rios C, Montgomery MT, Eng C, Elhawary JR, Mak ACY, Hu D, Huntsman S, Salazar S, Feriani L, Fairbanks-Mahnke A, Zinnen GL, Michel CR, Gomez J, Zhang X, Medina V, Chu HW, Cicuta P, Gordon ED, Zeitlin P, Ortega VE, Reisdorph N, Dunican EM, Tang M, Elicker BM, Henry TS, Bleecker ER, Castro M, Erzurum SC, Israel E, Levy BD, Mauger DT, Meyers DA, Sumino K, Gierada DS, Hastie AT, Moore WC, Denlinger LC, Jarjour NN, Schiebler ML, Wenzel SE, Woodruff PG, Rodriguez-Santana J, Pearson CG, Burchard EG, Fahy JV, Seibold MA. Everman JL, et al. Among authors: peters mc. Nat Commun. 2024 May 9;15(1):3900. doi: 10.1038/s41467-024-48034-5. Nat Commun. 2024. PMID: 38724552 Free PMC article.
4,063 results