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The Autophagy-Initiating Kinase ULK1 Controls RIPK1-Mediated Cell Death.
Wu W, Wang X, Berleth N, Deitersen J, Wallot-Hieke N, Böhler P, Schlütermann D, Stuhldreier F, Cox J, Schmitz K, Seggewiß S, Peter C, Kasof G, Stefanski A, Stühler K, Tschapek A, Gödecke A, Stork B. Wu W, et al. Among authors: peter c. Cell Rep. 2020 Apr 21;31(3):107547. doi: 10.1016/j.celrep.2020.107547. Cell Rep. 2020. PMID: 32320653 Free article.
PDK1 controls upstream PI3K expression and PIP3 generation.
Dieterle AM, Böhler P, Keppeler H, Alers S, Berleth N, Drießen S, Hieke N, Pietkiewicz S, Löffler AS, Peter C, Gray A, Leslie NR, Shinohara H, Kurosaki T, Engelke M, Wienands J, Bonin M, Wesselborg S, Stork B. Dieterle AM, et al. Among authors: peter c. Oncogene. 2014 Jun 5;33(23):3043-53. doi: 10.1038/onc.2013.266. Epub 2013 Jul 29. Oncogene. 2014. PMID: 23893244
Deubiquitinase inhibition by WP1130 leads to ULK1 aggregation and blockade of autophagy.
Drießen S, Berleth N, Friesen O, Löffler AS, Böhler P, Hieke N, Stuhldreier F, Peter C, Schink KO, Schultz SW, Stenmark H, Holland P, Simonsen A, Wesselborg S, Stork B. Drießen S, et al. Among authors: peter c. Autophagy. 2015;11(9):1458-70. doi: 10.1080/15548627.2015.1067359. Autophagy. 2015. PMID: 26207339 Free PMC article.
Expression of a ULK1/2 binding-deficient ATG13 variant can partially restore autophagic activity in ATG13-deficient cells.
Hieke N, Löffler AS, Kaizuka T, Berleth N, Böhler P, Drießen S, Stuhldreier F, Friesen O, Assani K, Schmitz K, Peter C, Diedrich B, Dengjel J, Holland P, Simonsen A, Wesselborg S, Mizushima N, Stork B. Hieke N, et al. Among authors: peter c. Autophagy. 2015;11(9):1471-83. doi: 10.1080/15548627.2015.1068488. Autophagy. 2015. PMID: 26213203 Free PMC article.
Systematic analysis of ATG13 domain requirements for autophagy induction.
Wallot-Hieke N, Verma N, Schlütermann D, Berleth N, Deitersen J, Böhler P, Stuhldreier F, Wu W, Seggewiß S, Peter C, Gohlke H, Mizushima N, Stork B. Wallot-Hieke N, et al. Among authors: peter c. Autophagy. 2018;14(5):743-763. doi: 10.1080/15548627.2017.1387342. Epub 2018 Mar 21. Autophagy. 2018. PMID: 29173006 Free PMC article.
Targeting urothelial carcinoma cells by combining cisplatin with a specific inhibitor of the autophagy-inducing class III PtdIns3K complex.
Schlütermann D, Skowron MA, Berleth N, Böhler P, Deitersen J, Stuhldreier F, Wallot-Hieke N, Wu W, Peter C, Hoffmann MJ, Niegisch G, Stork B. Schlütermann D, et al. Among authors: peter c. Urol Oncol. 2018 Apr;36(4):160.e1-160.e13. doi: 10.1016/j.urolonc.2017.11.021. Epub 2017 Dec 21. Urol Oncol. 2018. PMID: 29276062 Free article.
An essential role of the autophagy activating kinase ULK1 in snRNP biogenesis.
Schmitz K, Cox J, Esser LM, Voss M, Sander K, Löffler A, Hillebrand F, Erkelenz S, Schaal H, Kähne T, Klinker S, Zhang T, Nagel-Steger L, Willbold D, Seggewiß S, Schlütermann D, Stork B, Grimmler M, Wesselborg S, Peter C. Schmitz K, et al. Among authors: peter c. Nucleic Acids Res. 2021 Jun 21;49(11):6437-6455. doi: 10.1093/nar/gkab452. Nucleic Acids Res. 2021. PMID: 34096600 Free PMC article.
FIP200 controls the TBK1 activation threshold at SQSTM1/p62-positive condensates.
Schlütermann D, Berleth N, Deitersen J, Wallot-Hieke N, Friesen O, Wu W, Stuhldreier F, Sun Y, Berning L, Friedrich A, Mendiburo MJ, Peter C, Wiek C, Hanenberg H, Stefanski A, Stühler K, Stork B. Schlütermann D, et al. Among authors: peter c. Sci Rep. 2021 Jul 5;11(1):13863. doi: 10.1038/s41598-021-92408-4. Sci Rep. 2021. PMID: 34226595 Free PMC article.
560 results