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The arginine methyltransferase PRMT7 promotes extravasation of monocytes resulting in tissue injury in COPD.
Nat Commun. 2022 Mar 14;13(1):1303. doi: 10.1038/s41467-022-28809-4.
Nat Commun. 2022.
PMID: 35288557
Free PMC article.
Ex vivo tissue perturbations coupled to single-cell RNA-seq reveal multilineage cell circuit dynamics in human lung fibrogenesis.
Lang NJ, Gote-Schniering J, Porras-Gonzalez D, Yang L, De Sadeleer LJ, Jentzsch RC, Shitov VA, Zhou S, Ansari M, Agami A, Mayr CH, Hooshiar Kashani B, Chen Y, Heumos L, Pestoni JC, Molnar ES, Geeraerts E, Anquetil V, Saniere L, Wögrath M, Gerckens M, Lehmann M, Yildirim AÖ, Hatz R, Kneidinger N, Behr J, Wuyts WA, Stoleriu MG, Luecken MD, Theis FJ, Burgstaller G, Schiller HB.
Lang NJ, et al. Among authors: pestoni jc.
Sci Transl Med. 2023 Dec 6;15(725):eadh0908. doi: 10.1126/scitranslmed.adh0908. Epub 2023 Dec 6.
Sci Transl Med. 2023.
PMID: 38055803
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Sfrp1 inhibits lung fibroblast invasion during transition to injury-induced myofibroblasts.
Mayr CH, Sengupta A, Asgharpour S, Ansari M, Pestoni JC, Ogar P, Angelidis I, Liontos A, Rodriguez-Castillo JA, Lang NJ, Strunz M, Porras-Gonzalez D, Gerckens M, De Sadeleer LJ, Oehrle B, Viteri-Alvarez V, Fernandez IE, Tallquist M, Irmler M, Beckers J, Eickelberg O, Stoleriu GM, Behr J, Kneidinger N, Wuyts WA, Wasnick RM, Yildirim AÖ, Ahlbrecht K, Morty RE, Samakovlis C, Theis FJ, Burgstaller G, Schiller HB.
Mayr CH, et al. Among authors: pestoni jc.
Eur Respir J. 2024 Feb 8;63(2):2301326. doi: 10.1183/13993003.01326-2023. Print 2024 Feb.
Eur Respir J. 2024.
PMID: 38212077
Free PMC article.
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Peroxynitrite nitration of Tyr 56 in Hsp90 induces PC12 cell death through P2X7R-dependent PTEN activation.
Jandy M, Noor A, Nelson P, Dennys CN, Karabinas IM, Pestoni JC, Singh GD, Luc L, Devyldere R, Perdomo N, Mitchell CE, Adams L, Fuse MA, Mendoza FA, Marean-Reardon CL, Mehl RA, Estevez AG, Franco MC.
Jandy M, et al. Among authors: pestoni jc.
Redox Biol. 2022 Apr;50:102247. doi: 10.1016/j.redox.2022.102247. Epub 2022 Jan 26.
Redox Biol. 2022.
PMID: 35121403
Free PMC article.
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Peroxynitrite supports a metabolic reprogramming in merlin-deficient Schwann cells and promotes cell survival.
Pestoni JC, Klingeman Plati S, Valdivia Camacho OD, Fuse MA, Onatunde M, Sparrow NA, Karajannis MA, Fernández-Valle C, Franco MC.
Pestoni JC, et al.
J Biol Chem. 2019 Jul 26;294(30):11354-11368. doi: 10.1074/jbc.RA118.007152. Epub 2019 Jun 6.
J Biol Chem. 2019.
PMID: 31171721
Free PMC article.
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