Pessoa-Mahana CD - Search Results

1

Extended N-Arylsulfonylindoles as 5-HT₆ Receptor Antagonists: Design, Synthesis & Biological Evaluation.

Vera G, Lagos CF, Almendras S, Hebel D, Flores F, Valle-Corvalán G, Pessoa-Mahana CD, Mella-Raipán J, Montecinos R, Recabarren-Gajardo G. Vera G, et al. Molecules. 2016 Aug 16;21(8):1070. doi: 10.3390/molecules21081070. Molecules. 2016. PMID: 27537868 Free PMC article.

2

Computational modeling study of functional microdomains in cannabinoid receptor type 1.

Gonzalez A, Duran LS, Araya-Secchi R, Garate JA, Pessoa-Mahana CD, Lagos CF, Perez-Acle T. Gonzalez A, et al. Bioorg Med Chem. 2008 Apr 15;16(8):4378-89. doi: 10.1016/j.bmc.2008.02.070. Epub 2008 Feb 26. Bioorg Med Chem. 2008. PMID: 18342519

3

Antioxidant capacity of pure compounds and complex mixtures evaluated by the ORAC-pyrogallol red assay in the presence of Triton X-100 micelles.

Romero M, Rojano B, Mella-Raipán J, Pessoa-Mahana CD, Lissi E, López-Alarcón C. Romero M, et al. Molecules. 2010 Sep 1;15(9):6152-67. doi: 10.3390/molecules15096152. Molecules. 2010. PMID: 20877213 Free PMC article.

4

Evaluation of the membrane permeability (PAMPA and skin) of benzimidazoles with potential cannabinoid activity and their relation with the Biopharmaceutics Classification System (BCS).

Alvarez-Figueroa MJ, Pessoa-Mahana CD, Palavecino-González ME, Mella-Raipán J, Espinosa-Bustos C, Lagos-Muñoz ME. Alvarez-Figueroa MJ, et al. AAPS PharmSciTech. 2011 Jun;12(2):573-8. doi: 10.1208/s12249-011-9622-1. Epub 2011 May 4. AAPS PharmSciTech. 2011. PMID: 21538213 Free PMC article.

5

Synthesis, docking studies and biological evaluation of benzo[b]thiophen-2-yl-3-(4-arylpiperazin-1-yl)-propan-1-one derivatives on 5-HT1A serotonin receptors.

Pessoa-Mahana H, Recabarren-Gajardo G, Temer JF, Zapata-Torres G, Pessoa-Mahana CD, Barría CS, Araya-Maturana R. Pessoa-Mahana H, et al. Molecules. 2012 Feb 3;17(2):1388-407. doi: 10.3390/molecules17021388. Molecules. 2012. PMID: 22306829 Free PMC article.

6

Synthesis, 5-hydroxytryptamine1A receptor affinity and docking studies of 3-[3-(4-aryl-1-piperazinyl)-propyl]-1H-indole derivatives.

Pessoa-Mahana H, Núñez CU, Araya-Maturana R, Barría CS, Zapata-Torres G, Pessoa-Mahana CD, Iturriaga-Vasquez P, Mella-Raipán J, Reyes-Parada M, Celis-Barros C. Pessoa-Mahana H, et al. Chem Pharm Bull (Tokyo). 2012;60(5):632-8. doi: 10.1248/cpb.60.632. Chem Pharm Bull (Tokyo). 2012. PMID: 22689401 Free article.

7

Design, synthesis, binding and docking-based 3D-QSAR studies of 2-pyridylbenzimidazoles--a new family of high affinity CB1 cannabinoid ligands.

Mella-Raipán JA, Lagos CF, Recabarren-Gajardo G, Espinosa-Bustos C, Romero-Parra J, Pessoa-Mahana H, Iturriaga-Vásquez P, Pessoa-Mahana CD. Mella-Raipán JA, et al. Molecules. 2013 Apr 4;18(4):3972-4001. doi: 10.3390/molecules18043972. Molecules. 2013. PMID: 23558540 Free PMC article.

8

Synthesis, docking and pharmacological evaluation of novel homo- and hetero-bis 3-piperazinylpropylindole derivatives at SERT and 5-HT1A receptor.

Pessoa-Mahana H, González-Lira C, Fierro A, Zapata-Torres G, Pessoa-Mahana CD, Ortiz-Severin J, Iturriaga-Vásquez P, Reyes-Parada M, Silva-Matus P, Saitz-Barría C, Araya-Maturana R. Pessoa-Mahana H, et al. Bioorg Med Chem. 2013 Dec 15;21(24):7604-11. doi: 10.1016/j.bmc.2013.10.036. Epub 2013 Nov 6. Bioorg Med Chem. 2013. PMID: 24262884

9

Synthesis and biological screening of novel indolalkyl arenes targeting the serotonine transporter.

Ojeda-Gómez C, Pessoa-Mahana H, Iturriaga-Vásquez P, Pessoa-Mahana CD, Recabarren-Gajardo G, Méndez-Rojas C. Ojeda-Gómez C, et al. Arch Pharm (Weinheim). 2014 Mar;347(3):174-84. doi: 10.1002/ardp.201300321. Epub 2013 Dec 11. Arch Pharm (Weinheim). 2014. PMID: 24339227

10

Design, synthesis, biological evaluation and binding mode modeling of benzimidazole derivatives targeting the cannabinoid receptor type 1.

Espinosa-Bustos C, Lagos CF, Romero-Parra J, Zárate AM, Mella-Raipán J, Pessoa-Mahana H, Recabarren-Gajardo G, Iturriaga-Vásquez P, Tapia RA, Pessoa-Mahana CD. Espinosa-Bustos C, et al. Arch Pharm (Weinheim). 2015 Feb;348(2):81-8. doi: 10.1002/ardp.201400201. Epub 2015 Jan 13. Arch Pharm (Weinheim). 2015. PMID: 25641513

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