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1,2,3-triazole-, arylamino- and thio-substituted 1,4-naphthoquinones: potent antitumor activity, electrochemical aspects, and bioisosteric replacement of C-ring-modified lapachones.
da Cruz EH, Hussene CM, Dias GG, Diogo EB, de Melo IM, Rodrigues BL, da Silva MG, Valença WO, Camara CA, de Oliveira RN, de Paiva YG, Goulart MO, Cavalcanti BC, Pessoa C, da Silva Júnior EN. da Cruz EH, et al. Among authors: pessoa c. Bioorg Med Chem. 2014 Mar 1;22(5):1608-19. doi: 10.1016/j.bmc.2014.01.033. Epub 2014 Jan 31. Bioorg Med Chem. 2014. PMID: 24530030 Free article.
Synthesis and antitumor activity of selenium-containing quinone-based triazoles possessing two redox centres, and their mechanistic insights.
da Cruz EHG, Silvers MA, Jardim GAM, Resende JM, Cavalcanti BC, Bomfim IS, Pessoa C, de Simone CA, Botteselle GV, Braga AL, Nair DK, Namboothiri INN, Boothman DA, da Silva Júnior EN. da Cruz EHG, et al. Among authors: pessoa c. Eur J Med Chem. 2016 Oct 21;122:1-16. doi: 10.1016/j.ejmech.2016.06.019. Epub 2016 Jun 14. Eur J Med Chem. 2016. PMID: 27341379 Free PMC article.
On the synthesis of quinone-based BODIPY hybrids: New insights on antitumor activity and mechanism of action in cancer cells.
Gontijo TB, de Freitas RP, Emery FS, Pedrosa LF, Vieira Neto JB, Cavalcanti BC, Pessoa C, King A, de Moliner F, Vendrell M, da Silva Júnior EN. Gontijo TB, et al. Among authors: pessoa c. Bioorg Med Chem Lett. 2017 Sep 15;27(18):4446-4456. doi: 10.1016/j.bmcl.2017.08.007. Epub 2017 Aug 4. Bioorg Med Chem Lett. 2017. PMID: 28818447 Free article.
Quinonoid compounds via reactions of lawsone and 2-aminonaphthoquinone with α-bromonitroalkenes and nitroallylic acetates: Structural diversity by C-ring modification and cytotoxic evaluation against cancer cells.
Baiju TV, Almeida RG, Sivanandan ST, de Simone CA, Brito LM, Cavalcanti BC, Pessoa C, Namboothiri INN, da Silva Júnior EN. Baiju TV, et al. Among authors: pessoa c. Eur J Med Chem. 2018 May 10;151:686-704. doi: 10.1016/j.ejmech.2018.03.079. Epub 2018 Apr 5. Eur J Med Chem. 2018. PMID: 29660689
The evaluation of quinonoid compounds against Trypanosoma cruzi: synthesis of imidazolic anthraquinones, nor-beta-lapachone derivatives and beta-lapachone-based 1,2,3-triazoles.
da Silva EN Jr, Guimarães TT, Menna-Barreto RF, Pinto Mdo C, de Simone CA, Pessoa C, Cavalcanti BC, Sabino JR, Andrade CK, Goulart MO, de Castro SL, Pinto AV. da Silva EN Jr, et al. Among authors: pessoa c. Bioorg Med Chem. 2010 May 1;18(9):3224-30. doi: 10.1016/j.bmc.2010.03.029. Epub 2010 Mar 16. Bioorg Med Chem. 2010. PMID: 20378360 Free article.
Synthesis and evaluation of quinonoid compounds against tumor cell lines.
da Silva EN Jr, Cavalcanti BC, Guimarães TT, Pinto Mdo C, Cabral IO, Pessoa C, Costa-Lotufo LV, de Moraes MO, de Andrade CK, Dos Santos MR, de Simone CA, Goulart MO, Pinto AV. da Silva EN Jr, et al. Among authors: pessoa c. Eur J Med Chem. 2011 Jan;46(1):399-410. doi: 10.1016/j.ejmech.2010.11.006. Epub 2010 Nov 9. Eur J Med Chem. 2011. PMID: 21115213 Free article.
348 results