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Page 1
Discovery and synthesis of HIV integrase inhibitors: development of potent and orally bioavailable N-methyl pyrimidones.
Gardelli C, Nizi E, Muraglia E, Crescenzi B, Ferrara M, Orvieto F, Pace P, Pescatore G, Poma M, Ferreira Mdel R, Scarpelli R, Homnick CF, Ikemoto N, Alfieri A, Verdirame M, Bonelli F, Paz OG, Taliani M, Monteagudo E, Pesci S, Laufer R, Felock P, Stillmock KA, Hazuda D, Rowley M, Summa V. Gardelli C, et al. Among authors: pesci s. J Med Chem. 2007 Oct 4;50(20):4953-75. doi: 10.1021/jm0704705. Epub 2007 Sep 8. J Med Chem. 2007. PMID: 17824681
Inhibitors of the hepatitis C virus NS3 protease with basic amine functionality at the P3-amino acid N-terminus: discovery and optimization of a new series of P2-P4 macrocycles.
Harper S, Ferrara M, Crescenzi B, Pompei M, Palumbi MC, DiMuzio JM, Donghi M, Fiore F, Koch U, Liverton NJ, Pesci S, Petrocchi A, Rowley M, Summa V, Gardelli C. Harper S, et al. Among authors: pesci s. J Med Chem. 2009 Aug 13;52(15):4820-37. doi: 10.1021/jm900372w. J Med Chem. 2009. PMID: 19624135
Discovery of 2-{4-[(3S)-piperidin-3-yl]phenyl}-2H-indazole-7-carboxamide (MK-4827): a novel oral poly(ADP-ribose)polymerase (PARP) inhibitor efficacious in BRCA-1 and -2 mutant tumors.
Jones P, Altamura S, Boueres J, Ferrigno F, Fonsi M, Giomini C, Lamartina S, Monteagudo E, Ontoria JM, Orsale MV, Palumbi MC, Pesci S, Roscilli G, Scarpelli R, Schultz-Fademrecht C, Toniatti C, Rowley M. Jones P, et al. Among authors: pesci s. J Med Chem. 2009 Nov 26;52(22):7170-85. doi: 10.1021/jm901188v. J Med Chem. 2009. PMID: 19873981
Protection of homologous and heterologous boosters after primary schemes of rAd26-rAd5, ChAdOx1 nCoV-19 and BBIBP-CorV during the omicron outbreak in adults of 50 years and older in Argentina: a test-negative case-control study.
González S, Olszevicki S, Gaiano A, Salazar M, Regairaz L, Varela Baino AN, Bartel E, Varela T, González Martínez VV, Pesci S, Marín L, Irassar JI, Ceriani L, Garcia E, Kreplak N, Estenssoro E, Marsico F. González S, et al. Among authors: pesci s. Lancet Reg Health Am. 2023 Sep 28;27:100607. doi: 10.1016/j.lana.2023.100607. eCollection 2023 Nov. Lancet Reg Health Am. 2023. PMID: 37808936 Free PMC article.
20 results