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The displacement of frataxin from the mitochondrial cristae correlates with abnormal respiratory supercomplexes formation and bioenergetic defects in cells of Friedreich ataxia patients.
Doni D, Rigoni G, Palumbo E, Baschiera E, Peruzzo R, De Rosa E, Caicci F, Passerini L, Bettio D, Russo A, Szabò I, Soriano ME, Salviati L, Costantini P. Doni D, et al. Among authors: peruzzo r. FASEB J. 2021 Mar;35(3):e21362. doi: 10.1096/fj.202000524RR. FASEB J. 2021. PMID: 33629768
Insight into the mechanism of cytotoxicity of membrane-permeant psoralenic Kv1.3 channel inhibitors by chemical dissection of a novel member of the family.
Peruzzo R, Mattarei A, Azzolini M, Becker-Flegler KA, Romio M, Rigoni G, Carrer A, Biasutto L, Parrasia S, Kadow S, Managò A, Urbani A, Rossa A, Semenzato G, Soriano ME, Trentin L, Ahmad S, Edwards M, Gulbins E, Paradisi C, Zoratti M, Leanza L, Szabò I. Peruzzo R, et al. Redox Biol. 2020 Oct;37:101705. doi: 10.1016/j.redox.2020.101705. Epub 2020 Sep 6. Redox Biol. 2020. PMID: 33007503 Free PMC article.
Corrigendum to "Insight into the mechanism of cytotoxicity of membrane-permeant psoralenic Kv1.3 channel inhibitors by chemical dissection of a novel member of the family" [Redox Biol. 37 (2020 Sep 6) 101705-101721].
Peruzzo R, Mattarei A, Azzolini M, Becker-Flegler KA, Romio M, Rigoni G, Carrer A, Biasutto L, Parrasia S, Kadow S, Managò A, Urbani A, Rossa A, Semenzato G, Soriano ME, Trentin L, Ahmad S, Edwards M, Gulbins E, Paradisi C, Zoratti M, Leanza L, Szabò I. Peruzzo R, et al. Redox Biol. 2021 Sep;45:102036. doi: 10.1016/j.redox.2021.102036. Epub 2021 Jun 29. Redox Biol. 2021. PMID: 34210643 Free PMC article. No abstract available.
Mitochondrial apoptosis is induced by Alkoxy phenyl-1-propanone derivatives through PP2A-mediated dephosphorylation of Bad and Foxo3A in CLL.
Pagano MA, Tibaldi E, Molino P, Frezzato F, Trimarco V, Facco M, Zagotto G, Ribaudo G, Leanza L, Peruzzo R, Szabò I, Visentin A, Frasson M, Semenzato G, Trentin L, Brunati AM. Pagano MA, et al. Among authors: peruzzo r. Leukemia. 2019 May;33(5):1148-1160. doi: 10.1038/s41375-018-0288-5. Epub 2018 Oct 23. Leukemia. 2019. PMID: 30353029
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