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Crowdsourcing digital health measures to predict Parkinson's disease severity: the Parkinson's Disease Digital Biomarker DREAM Challenge.
Sieberts SK, Schaff J, Duda M, Pataki BÁ, Sun M, Snyder P, Daneault JF, Parisi F, Costante G, Rubin U, Banda P, Chae Y, Chaibub Neto E, Dorsey ER, Aydın Z, Chen A, Elo LL, Espino C, Glaab E, Goan E, Golabchi FN, Görmez Y, Jaakkola MK, Jonnagaddala J, Klén R, Li D, McDaniel C, Perrin D, Perumal TM, Rad NM, Rainaldi E, Sapienza S, Schwab P, Shokhirev N, Venäläinen MS, Vergara-Diaz G, Zhang Y; Parkinson’s Disease Digital Biomarker Challenge Consortium; Wang Y, Guan Y, Brunner D, Bonato P, Mangravite LM, Omberg L. Sieberts SK, et al. Among authors: perumal tm. NPJ Digit Med. 2021 Mar 19;4(1):53. doi: 10.1038/s41746-021-00414-7. NPJ Digit Med. 2021. PMID: 33742069 Free PMC article.
Remote smartphone monitoring of Parkinson's disease and individual response to therapy.
Omberg L, Chaibub Neto E, Perumal TM, Pratap A, Tediarjo A, Adams J, Bloem BR, Bot BM, Elson M, Goldman SM, Kellen MR, Kieburtz K, Klein A, Little MA, Schneider R, Suver C, Tarolli C, Tanner CM, Trister AD, Wilbanks J, Dorsey ER, Mangravite LM. Omberg L, et al. Among authors: perumal tm. Nat Biotechnol. 2022 Apr;40(4):480-487. doi: 10.1038/s41587-021-00974-9. Epub 2021 Aug 9. Nat Biotechnol. 2022. PMID: 34373643
Identifying drug targets for neurological and psychiatric disease via genetics and the brain transcriptome.
Baird DA, Liu JZ, Zheng J, Sieberts SK, Perumal T, Elsworth B, Richardson TG, Chen CY, Carrasquillo MM, Allen M, Reddy JS, De Jager PL, Ertekin-Taner N, Mangravite LM, Logsdon B, Estrada K, Haycock PC, Hemani G, Runz H, Smith GD, Gaunt TR; AMP-AD eQTL working group. Baird DA, et al. PLoS Genet. 2021 Jan 8;17(1):e1009224. doi: 10.1371/journal.pgen.1009224. eCollection 2021 Jan. PLoS Genet. 2021. PMID: 33417599 Free PMC article.
A community approach to mortality prediction in sepsis via gene expression analysis.
Sweeney TE, Perumal TM, Henao R, Nichols M, Howrylak JA, Choi AM, Bermejo-Martin JF, Almansa R, Tamayo E, Davenport EE, Burnham KL, Hinds CJ, Knight JC, Woods CW, Kingsmore SF, Ginsburg GS, Wong HR, Parnell GP, Tang B, Moldawer LL, Moore FE, Omberg L, Khatri P, Tsalik EL, Mangravite LM, Langley RJ. Sweeney TE, et al. Among authors: perumal tm. Nat Commun. 2018 Feb 15;9(1):694. doi: 10.1038/s41467-018-03078-2. Nat Commun. 2018. PMID: 29449546 Free PMC article.
Unsupervised Analysis of Transcriptomics in Bacterial Sepsis Across Multiple Datasets Reveals Three Robust Clusters.
Sweeney TE, Azad TD, Donato M, Haynes WA, Perumal TM, Henao R, Bermejo-Martin JF, Almansa R, Tamayo E, Howrylak JA, Choi A, Parnell GP, Tang B, Nichols M, Woods CW, Ginsburg GS, Kingsmore SF, Omberg L, Mangravite LM, Wong HR, Tsalik EL, Langley RJ, Khatri P. Sweeney TE, et al. Among authors: perumal tm. Crit Care Med. 2018 Jun;46(6):915-925. doi: 10.1097/CCM.0000000000003084. Crit Care Med. 2018. PMID: 29537985 Free PMC article.
Meta-Analysis of the Alzheimer's Disease Human Brain Transcriptome and Functional Dissection in Mouse Models.
Wan YW, Al-Ouran R, Mangleburg CG, Perumal TM, Lee TV, Allison K, Swarup V, Funk CC, Gaiteri C, Allen M, Wang M, Neuner SM, Kaczorowski CC, Philip VM, Howell GR, Martini-Stoica H, Zheng H, Mei H, Zhong X, Kim JW, Dawson VL, Dawson TM, Pao PC, Tsai LH, Haure-Mirande JV, Ehrlich ME, Chakrabarty P, Levites Y, Wang X, Dammer EB, Srivastava G, Mukherjee S, Sieberts SK, Omberg L, Dang KD, Eddy JA, Snyder P, Chae Y, Amberkar S, Wei W, Hide W, Preuss C, Ergun A, Ebert PJ, Airey DC, Mostafavi S, Yu L, Klein HU; Accelerating Medicines Partnership-Alzheimer’s Disease Consortium; Carter GW, Collier DA, Golde TE, Levey AI, Bennett DA, Estrada K, Townsend TM, Zhang B, Schadt E, De Jager PL, Price ND, Ertekin-Taner N, Liu Z, Shulman JM, Mangravite LM, Logsdon BA. Wan YW, et al. Among authors: perumal tm. Cell Rep. 2020 Jul 14;32(2):107908. doi: 10.1016/j.celrep.2020.107908. Cell Rep. 2020. PMID: 32668255 Free PMC article.
28 results