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Page 1
Latent human herpesvirus 6 is reactivated in CAR T cells.
Lareau CA, Yin Y, Maurer K, Sandor KD, Daniel B, Yagnik G, Peña J, Crawford JC, Spanjaart AM, Gutierrez JC, Haradhvala NJ, Riberdy JM, Abay T, Stickels RR, Verboon JM, Liu V, Buquicchio FA, Wang F, Southard J, Song R, Li W, Shrestha A, Parida L, Getz G, Maus MV, Li S, Moore A, Roberts ZJ, Ludwig LS, Talleur AC, Thomas PG, Dehghani H, Pertel T, Kundaje A, Gottschalk S, Roth TL, Kersten MJ, Wu CJ, Majzner RG, Satpathy AT. Lareau CA, et al. Among authors: pertel t. Nature. 2023 Nov;623(7987):608-615. doi: 10.1038/s41586-023-06704-2. Epub 2023 Nov 8. Nature. 2023. PMID: 37938768 Free PMC article.
Detection of chromosomal alteration after infusion of gene-edited allogeneic CAR T cells.
Sasu BJ, Opiteck GJ, Gopalakrishnan S, Kaimal V, Furmanak T, Huang D, Goswami A, He Y, Chen J, Nguyen A, Balakumaran A, Shah NN, Hamadani M, Bone KM, Prashad S, Bowen MA, Pertel T, Embree HD, Gidwani SG, Chang D, Moore A, Leonard M, Amado RG. Sasu BJ, et al. Among authors: pertel t. Mol Ther. 2023 Mar 1;31(3):676-685. doi: 10.1016/j.ymthe.2022.12.004. Epub 2022 Dec 14. Mol Ther. 2023. PMID: 36518079 Free PMC article.
Author Correction: CEACAM1 regulates TIM-3-mediated tolerance and exhaustion.
Huang YH, Zhu C, Kondo Y, Anderson AC, Gandhi A, Russell A, Dougan SK, Petersen BS, Melum E, Pertel T, Clayton KL, Raab M, Chen Q, Beauchemin N, Yazaki PJ, Pyzik M, Ostrowski MA, Glickman JN, Rudd CE, Ploegh HL, Franke A, Petsko GA, Kuchroo VK, Blumberg RS. Huang YH, et al. Among authors: pertel t. Nature. 2024 Feb;626(8001):E19. doi: 10.1038/s41586-024-07164-y. Nature. 2024. PMID: 38336833 No abstract available.
Gene-edited healthy donor CAR T cells show superior anti-tumour activity compared to CAR T cells derived from patients with lymphoma in an in vivo model of high-grade lymphoma.
Graham CE, Jozwik A, Quartey-Papafio R, Ioannou N, Metelo AM, Scala C, Dickson G, Stewart O, Almena-Carrasco M, Peranzoni E, Ramsay AG, Patten PEM, Pertel T, Farzaneh F, Dupouy S, Pepper A, Benjamin R. Graham CE, et al. Among authors: pertel t. Leukemia. 2021 Dec;35(12):3581-3584. doi: 10.1038/s41375-021-01324-z. Epub 2021 Jun 18. Leukemia. 2021. PMID: 34145373 Free PMC article. No abstract available.
Preclinical Evaluation of Allogeneic CAR T Cells Targeting BCMA for the Treatment of Multiple Myeloma.
Sommer C, Boldajipour B, Kuo TC, Bentley T, Sutton J, Chen A, Geng T, Dong H, Galetto R, Valton J, Pertel T, Juillerat A, Gariboldi A, Pascua E, Brown C, Chin SM, Sai T, Ni Y, Duchateau P, Smith J, Rajpal A, Van Blarcom T, Chaparro-Riggers J, Sasu BJ. Sommer C, et al. Among authors: pertel t. Mol Ther. 2019 Jun 5;27(6):1126-1138. doi: 10.1016/j.ymthe.2019.04.001. Epub 2019 Apr 8. Mol Ther. 2019. PMID: 31005597 Free PMC article.
Blockade of Tim-3 binding to phosphatidylserine and CEACAM1 is a shared feature of anti-Tim-3 antibodies that have functional efficacy.
Sabatos-Peyton CA, Nevin J, Brock A, Venable JD, Tan DJ, Kassam N, Xu F, Taraszka J, Wesemann L, Pertel T, Acharya N, Klapholz M, Etminan Y, Jiang X, Huang YH, Blumberg RS, Kuchroo VK, Anderson AC. Sabatos-Peyton CA, et al. Among authors: pertel t. Oncoimmunology. 2017 Nov 9;7(2):e1385690. doi: 10.1080/2162402X.2017.1385690. eCollection 2018. Oncoimmunology. 2017. PMID: 29308307 Free PMC article.
Open conformers of HLA-F are high-affinity ligands of the activating NK-cell receptor KIR3DS1.
Garcia-Beltran WF, Hölzemer A, Martrus G, Chung AW, Pacheco Y, Simoneau CR, Rucevic M, Lamothe-Molina PA, Pertel T, Kim TE, Dugan H, Alter G, Dechanet-Merville J, Jost S, Carrington M, Altfeld M. Garcia-Beltran WF, et al. Among authors: pertel t. Nat Immunol. 2016 Sep;17(9):1067-74. doi: 10.1038/ni.3513. Epub 2016 Jul 25. Nat Immunol. 2016. PMID: 27455421 Free PMC article.
45 results