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Clinical and functional consequences of GRIA variants in patients with neurological diseases.
XiangWei W, Perszyk RE, Liu N, Xu Y, Bhattacharya S, Shaulsky GH, Smith-Hicks C, Fatemi A, Fry AE, Chandler K, Wang T, Vogt J, Cohen JS, Paciorkowski AR, Poduri A, Zhang Y, Wang S, Wang Y, Zhai Q, Fang F, Leng J, Garber K, Myers SJ, Jauss RT, Park KL, Benke TA, Lemke JR, Yuan H, Jiang Y, Traynelis SF. XiangWei W, et al. Among authors: perszyk re. Cell Mol Life Sci. 2023 Nov 3;80(11):345. doi: 10.1007/s00018-023-04991-6. Cell Mol Life Sci. 2023. PMID: 37921875
A novel class of negative allosteric modulators of NMDA receptor function.
Katzman BM, Perszyk RE, Yuan H, Tahirovic YA, Sotimehin AE, Traynelis SF, Liotta DC. Katzman BM, et al. Among authors: perszyk re. Bioorg Med Chem Lett. 2015 Dec 1;25(23):5583-8. doi: 10.1016/j.bmcl.2015.10.046. Epub 2015 Oct 19. Bioorg Med Chem Lett. 2015. PMID: 26525866 Free PMC article.
NMDA Receptors in the Central Nervous System.
Hansen KB, Yi F, Perszyk RE, Menniti FS, Traynelis SF. Hansen KB, et al. Among authors: perszyk re. Methods Mol Biol. 2017;1677:1-80. doi: 10.1007/978-1-4939-7321-7_1. Methods Mol Biol. 2017. PMID: 28986865 Free PMC article.
Structure, function, and allosteric modulation of NMDA receptors.
Hansen KB, Yi F, Perszyk RE, Furukawa H, Wollmuth LP, Gibb AJ, Traynelis SF. Hansen KB, et al. Among authors: perszyk re. J Gen Physiol. 2018 Aug 6;150(8):1081-1105. doi: 10.1085/jgp.201812032. Epub 2018 Jul 23. J Gen Physiol. 2018. PMID: 30037851 Free PMC article. Review.
Biased modulators of NMDA receptors control channel opening and ion selectivity.
Perszyk RE, Swanger SA, Shelley C, Khatri A, Fernandez-Cuervo G, Epplin MP, Zhang J, Le P, Bülow P, Garnier-Amblard E, Gangireddy PKR, Bassell GJ, Yuan H, Menaldino DS, Liotta DC, Liebeskind LS, Traynelis SF. Perszyk RE, et al. Nat Chem Biol. 2020 Feb;16(2):188-196. doi: 10.1038/s41589-019-0449-5. Epub 2020 Jan 20. Nat Chem Biol. 2020. PMID: 31959964 Free PMC article.
Distinct GluN1 and GluN2 Structural Determinants for Subunit-Selective Positive Allosteric Modulation of N-Methyl-d-aspartate Receptors.
Strong KL, Epplin MP, Ogden KK, Burger PB, Kaiser TM, Wilding TJ, Kusumoto H, Camp CR, Shaulsky G, Bhattacharya S, Perszyk RE, Menaldino DS, McDaniel MJ, Zhang J, Le P, Banke TG, Hansen KB, Huettner JE, Liotta DC, Traynelis SF. Strong KL, et al. Among authors: perszyk re. ACS Chem Neurosci. 2021 Jan 6;12(1):79-98. doi: 10.1021/acschemneuro.0c00561. Epub 2020 Dec 16. ACS Chem Neurosci. 2021. PMID: 33326224 Free PMC article.
26 results