Perrine SP - Search Results

1

Targeted fetal hemoglobin induction for treatment of beta hemoglobinopathies.

Perrine SP, Pace BS, Faller DV. Perrine SP, et al. Hematol Oncol Clin North Am. 2014 Apr;28(2):233-48. doi: 10.1016/j.hoc.2013.11.009. Hematol Oncol Clin North Am. 2014. PMID: 24589264 Review.

2

Benserazide racemate and enantiomers induce fetal globin gene expression in vivo: Studies to guide clinical development for beta thalassemia and sickle cell disease.

Pace BS, Perrine S, Li B, Makala L, Xu H, Takezaki M, Wolf RF, Wang A, Xu X, Huang J, Alimardanov A, Tawa GJ, Sangerman J, Faller A, Zheng W, Toney L, Haugabook SJ. Pace BS, et al. Blood Cells Mol Dis. 2021 Jul;89:102561. doi: 10.1016/j.bcmd.2021.102561. Epub 2021 Mar 12. Blood Cells Mol Dis. 2021. PMID: 33744514 Free PMC article.

3

Novel histone deacetylase inhibitor CT-101 induces γ-globin gene expression in sickle erythroid progenitors with targeted epigenetic effects.

Junker LH, Li B, Zhu X, Koti S, Cerbone RE, Hendrick CL, Sangerman J, Perrine S, Pace BS. Junker LH, et al. Blood Cells Mol Dis. 2022 Mar;93:102626. doi: 10.1016/j.bcmd.2021.102626. Epub 2021 Nov 17. Blood Cells Mol Dis. 2022. PMID: 34856533 Free PMC article.

4

Erythroid Kruppel-like factor (EKLF) is recruited to the gamma-globin gene promoter as a co-activator and is required for gamma-globin gene induction by short-chain fatty acid derivatives.

Perrine SP, Mankidy R, Boosalis MS, Bieker JJ, Faller DV. Perrine SP, et al. Eur J Haematol. 2009 Jun;82(6):466-76. doi: 10.1111/j.1600-0609.2009.01234.x. Epub 2009 Feb 5. Eur J Haematol. 2009. PMID: 19220418 Free PMC article.

5

Fetal globin gene inducers: novel agents and new potential.

Perrine SP, Castaneda SA, Chui DH, Faller DV, Berenson RJ, Siritanaratku N, Fucharoen S. Perrine SP, et al. Ann N Y Acad Sci. 2010 Aug;1202:158-64. doi: 10.1111/j.1749-6632.2010.05593.x. Ann N Y Acad Sci. 2010. PMID: 20712788 Free PMC article.

6

Novel therapeutic candidates, identified by molecular modeling, induce γ-globin gene expression in vivo.

Boosalis MS, Castaneda SA, Trudel M, Mabaera R, White GL, Lowrey CH, Emery DW, Mpollo MS, Shen L, Wargin WA, Bohacek R, Faller DV, Perrine SP. Boosalis MS, et al. Among authors: perrine sp. Blood Cells Mol Dis. 2011 Aug 15;47(2):107-16. doi: 10.1016/j.bcmd.2011.04.008. Blood Cells Mol Dis. 2011. PMID: 21641240 Free PMC article.

7

Therapeutic fetal-globin inducers reduce transcriptional repression in hemoglobinopathy erythroid progenitors through distinct mechanisms.

Dai Y, Sangerman J, Luo HY, Fucharoen S, Chui DH, Faller DV, Perrine SP. Dai Y, et al. Among authors: perrine sp. Blood Cells Mol Dis. 2016 Jan;56(1):62-9. doi: 10.1016/j.bcmd.2015.10.004. Epub 2015 Oct 27. Blood Cells Mol Dis. 2016. PMID: 26603726 Free PMC article.

8

Novel Inducers of Fetal Globin Identified through High Throughput Screening (HTS) Are Active In Vivo in Anemic Baboons and Transgenic Mice.

Boosalis MS, Sangerman JI, White GL, Wolf RF, Shen L, Dai Y, White E, Makala LH, Li B, Pace BS, Nouraie M, Faller DV, Perrine SP. Boosalis MS, et al. Among authors: perrine sp. PLoS One. 2015 Dec 29;10(12):e0144660. doi: 10.1371/journal.pone.0144660. eCollection 2015. PLoS One. 2015. PMID: 26713848 Free PMC article.

9

Butyrate in the treatment of sickle cell disease and beta-thalassemia.

Faller DV, Perrine SP. Faller DV, et al. Among authors: perrine sp. Curr Opin Hematol. 1995 Mar;2(2):109-17. doi: 10.1097/00062752-199502020-00002. Curr Opin Hematol. 1995. PMID: 9371980 Review.

10

Short-chain fatty acid derivatives induce fetal globin expression and erythropoiesis in vivo.

Pace BS, White GL, Dover GJ, Boosalis MS, Faller DV, Perrine SP. Pace BS, et al. Among authors: perrine sp. Blood. 2002 Dec 15;100(13):4640-8. doi: 10.1182/blood-2002-02-0353. Epub 2002 Aug 15. Blood. 2002. PMID: 12393583 Free PMC article.

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