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Page 1
Preclinical Evaluation of a Lentiviral Vector for Huntingtin Silencing.
Cambon K, Zimmer V, Martineau S, Gaillard MC, Jarrige M, Bugi A, Miniarikova J, Rey M, Hassig R, Dufour N, Auregan G, Hantraye P, Perrier AL, Déglon N. Cambon K, et al. Among authors: perrier al. Mol Ther Methods Clin Dev. 2017 May 11;5:259-276. doi: 10.1016/j.omtm.2017.05.001. eCollection 2017 Jun 16. Mol Ther Methods Clin Dev. 2017. PMID: 28603746 Free PMC article.
The postischemic environment differentially impacts teratoma or tumor formation after transplantation of human embryonic stem cell-derived neural progenitors.
Seminatore C, Polentes J, Ellman D, Kozubenko N, Itier V, Tine S, Tritschler L, Brenot M, Guidou E, Blondeau J, Lhuillier M, Bugi A, Aubry L, Jendelova P, Sykova E, Perrier AL, Finsen B, Onteniente B. Seminatore C, et al. Among authors: perrier al. Stroke. 2010 Jan;41(1):153-9. doi: 10.1161/STROKEAHA.109.563015. Epub 2009 Nov 25. Stroke. 2010. PMID: 19940279
Early transcriptional changes linked to naturally occurring Huntington's disease mutations in neural derivatives of human embryonic stem cells.
Feyeux M, Bourgois-Rocha F, Redfern A, Giles P, Lefort N, Aubert S, Bonnefond C, Bugi A, Ruiz M, Deglon N, Jones L, Peschanski M, Allen ND, Perrier AL. Feyeux M, et al. Among authors: perrier al. Hum Mol Genet. 2012 Sep 1;21(17):3883-95. doi: 10.1093/hmg/dds216. Epub 2012 Jun 7. Hum Mol Genet. 2012. PMID: 22678061
High throughput screening for inhibitors of REST in neural derivatives of human embryonic stem cells reveals a chemical compound that promotes expression of neuronal genes.
Charbord J, Poydenot P, Bonnefond C, Feyeux M, Casagrande F, Brinon B, Francelle L, Aurégan G, Guillermier M, Cailleret M, Viegas P, Nicoleau C, Martinat C, Brouillet E, Cattaneo E, Peschanski M, Lechuga M, Perrier AL. Charbord J, et al. Among authors: perrier al. Stem Cells. 2013 Sep;31(9):1816-28. doi: 10.1002/stem.1430. Stem Cells. 2013. PMID: 23712629
Allele-specific silencing of mutant huntingtin in rodent brain and human stem cells.
Drouet V, Ruiz M, Zala D, Feyeux M, Auregan G, Cambon K, Troquier L, Carpentier J, Aubert S, Merienne N, Bourgois-Rocha F, Hassig R, Rey M, Dufour N, Saudou F, Perrier AL, Hantraye P, Déglon N. Drouet V, et al. Among authors: perrier al. PLoS One. 2014 Jun 13;9(6):e99341. doi: 10.1371/journal.pone.0099341. eCollection 2014. PLoS One. 2014. PMID: 24926995 Free PMC article.
Human ESC-derived dopamine neurons show similar preclinical efficacy and potency to fetal neurons when grafted in a rat model of Parkinson's disease.
Grealish S, Diguet E, Kirkeby A, Mattsson B, Heuer A, Bramoulle Y, Van Camp N, Perrier AL, Hantraye P, Björklund A, Parmar M. Grealish S, et al. Among authors: perrier al. Cell Stem Cell. 2014 Nov 6;15(5):653-65. doi: 10.1016/j.stem.2014.09.017. Epub 2014 Nov 6. Cell Stem Cell. 2014. PMID: 25517469 Free PMC article.
The Self-Inactivating KamiCas9 System for the Editing of CNS Disease Genes.
Merienne N, Vachey G, de Longprez L, Meunier C, Zimmer V, Perriard G, Canales M, Mathias A, Herrgott L, Beltraminelli T, Maulet A, Dequesne T, Pythoud C, Rey M, Pellerin L, Brouillet E, Perrier AL, du Pasquier R, Déglon N. Merienne N, et al. Among authors: perrier al. Cell Rep. 2017 Sep 19;20(12):2980-2991. doi: 10.1016/j.celrep.2017.08.075. Cell Rep. 2017. PMID: 28930690 Free article.
49 results