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Human Bone Marrow Organoids for Disease Modeling, Discovery, and Validation of Therapeutic Targets in Hematologic Malignancies.
Khan AO, Rodriguez-Romera A, Reyat JS, Olijnik AA, Colombo M, Wang G, Wen WX, Sousos N, Murphy LC, Grygielska B, Perrella G, Mahony CB, Ling RE, Elliott NE, Karali CS, Stone AP, Kemble S, Cutler EA, Fielding AK, Croft AP, Bassett D, Poologasundarampillai G, Roy A, Gooding S, Rayes J, Machlus KR, Psaila B. Khan AO, et al. Among authors: perrella g. Cancer Discov. 2023 Feb 6;13(2):364-385. doi: 10.1158/2159-8290.CD-22-0199. Cancer Discov. 2023. PMID: 36351055 Free PMC article.
Protein C or Protein S deficiency associates with paradoxically impaired platelet-dependent thrombus and fibrin formation under flow.
Brouns SLN, Tullemans BME, Bulato C, Perrella G, Campello E, Spiezia L, van Geffen JP, Kuijpers MJE, van Oerle R, Spronk HMH, van der Meijden PEJ, Simioni P, Heemskerk JWM. Brouns SLN, et al. Among authors: perrella g. Res Pract Thromb Haemost. 2022 Mar 7;6(2):e12678. doi: 10.1002/rth2.12678. eCollection 2022 Feb. Res Pract Thromb Haemost. 2022. PMID: 35284776 Free PMC article.
Role of Tyrosine Kinase Syk in Thrombus Stabilisation at High Shear.
Perrella G, Montague SJ, Brown HC, Garcia Quintanilla L, Slater A, Stegner D, Thomas M, Heemskerk JWM, Watson SP. Perrella G, et al. Int J Mol Sci. 2022 Jan 1;23(1):493. doi: 10.3390/ijms23010493. Int J Mol Sci. 2022. PMID: 35008919 Free PMC article.
S100A8/A9 drives the formation of procoagulant platelets through GPIbα.
Colicchia M, Schrottmaier WC, Perrella G, Reyat JS, Begum J, Slater A, Price J, Clark JC, Zhi Z, Simpson MJ, Bourne JH, Poulter NS, Khan AO, Nicolson PLR, Pugh M, Harrison P, Iqbal AJ, Rainger GE, Watson SP, Thomas MR, Mutch NJ, Assinger A, Rayes J. Colicchia M, et al. Among authors: perrella g. Blood. 2022 Dec 15;140(24):2626-2643. doi: 10.1182/blood.2021014966. Blood. 2022. PMID: 36026606 Free PMC article.
Hydroxychloroquine inhibits hemolysis-induced arterial thrombosis ex vivo and improves lung perfusion in hemin-treated mice.
Bourne JH, Perrella G, El-Awaisi J, Terry LV, Tinkova V, Hogg RL, Gant P, Grygielska B, Kalia N, Kavanagh D, Brill A, Dimitrov JD, Watson SP, Rayes J. Bourne JH, et al. Among authors: perrella g. J Thromb Haemost. 2024 Apr 24:S1538-7836(24)00226-5. doi: 10.1016/j.jtha.2024.04.008. Online ahead of print. J Thromb Haemost. 2024. PMID: 38670315 Free article.
65 results