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Mechanism of voltage sensing in Ca2+- and voltage-activated K+ (BK) channels.
Carrasquel-Ursulaez W, Segura I, Díaz-Franulic I, Echeverría F, Lorenzo-Ceballos Y, Espinoza N, Rojas M, Garate JA, Perozo E, Alvarez O, Gonzalez-Nilo FD, Latorre R. Carrasquel-Ursulaez W, et al. Among authors: perozo e. Proc Natl Acad Sci U S A. 2022 Jun 21;119(25):e2204620119. doi: 10.1073/pnas.2204620119. Epub 2022 Jun 15. Proc Natl Acad Sci U S A. 2022. PMID: 35704760 Free PMC article.
Crystal structure of full-length KcsA in its closed conformation.
Uysal S, Vásquez V, Tereshko V, Esaki K, Fellouse FA, Sidhu SS, Koide S, Perozo E, Kossiakoff A. Uysal S, et al. Among authors: perozo e. Proc Natl Acad Sci U S A. 2009 Apr 21;106(16):6644-9. doi: 10.1073/pnas.0810663106. Epub 2009 Apr 3. Proc Natl Acad Sci U S A. 2009. PMID: 19346472 Free PMC article.
Mechanism of activation gating in the full-length KcsA K+ channel.
Uysal S, Cuello LG, Cortes DM, Koide S, Kossiakoff AA, Perozo E. Uysal S, et al. Among authors: perozo e. Proc Natl Acad Sci U S A. 2011 Jul 19;108(29):11896-9. doi: 10.1073/pnas.1105112108. Epub 2011 Jul 5. Proc Natl Acad Sci U S A. 2011. PMID: 21730186 Free PMC article.
A repulsion mechanism explains magnesium permeation and selectivity in CorA.
Dalmas O, Sandtner W, Medovoy D, Frezza L, Bezanilla F, Perozo E. Dalmas O, et al. Among authors: perozo e. Proc Natl Acad Sci U S A. 2014 Feb 25;111(8):3002-7. doi: 10.1073/pnas.1319054111. Epub 2014 Feb 10. Proc Natl Acad Sci U S A. 2014. PMID: 24516146 Free PMC article.
Resting state of the human proton channel dimer in a lipid bilayer.
Li Q, Shen R, Treger JS, Wanderling SS, Milewski W, Siwowska K, Bezanilla F, Perozo E. Li Q, et al. Among authors: perozo e. Proc Natl Acad Sci U S A. 2015 Nov 3;112(44):E5926-35. doi: 10.1073/pnas.1515043112. Epub 2015 Oct 6. Proc Natl Acad Sci U S A. 2015. PMID: 26443860 Free PMC article.
121 results