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Probing the lithium-response pathway in hiPSCs implicates the phosphoregulatory set-point for a cytoskeletal modulator in bipolar pathogenesis.
Tobe BTD, Crain AM, Winquist AM, Calabrese B, Makihara H, Zhao WN, Lalonde J, Nakamura H, Konopaske G, Sidor M, Pernia CD, Yamashita N, Wada M, Inoue Y, Nakamura F, Sheridan SD, Logan RW, Brandel M, Wu D, Hunsberger J, Dorsett L, Duerr C, Basa RCB, McCarthy MJ, Udeshi ND, Mertins P, Carr SA, Rouleau GA, Mastrangelo L, Li J, Gutierrez GJ, Brill LM, Venizelos N, Chen G, Nye JS, Manji H, Price JH, McClung CA, Akiskal HS, Alda M, Chuang DM, Coyle JT, Liu Y, Teng YD, Ohshima T, Mikoshiba K, Sidman RL, Halpain S, Haggarty SJ, Goshima Y, Snyder EY. Tobe BTD, et al. Among authors: pernia cd. Proc Natl Acad Sci U S A. 2017 May 30;114(22):E4462-E4471. doi: 10.1073/pnas.1700111114. Epub 2017 May 12. Proc Natl Acad Sci U S A. 2017. PMID: 28500272 Free PMC article.
Clinical evidence that a dysregulated master neural network modulator may aid in diagnosing schizophrenia.
Nomoto M, Konopaske GT, Yamashita N, Aoki R, Jitsuki-Takahashi A, Nakamura H, Makihara H, Saito M, Saigusa Y, Nakamura F, Watanabe K, Baba T, Benes FM, Tobe BTD, Pernia CD, Coyle JT, Sidman RL, Hirayasu Y, Snyder EY, Goshima Y. Nomoto M, et al. Among authors: pernia cd. Proc Natl Acad Sci U S A. 2021 Aug 3;118(31):e2100032118. doi: 10.1073/pnas.2100032118. Proc Natl Acad Sci U S A. 2021. PMID: 34330827 Free PMC article.
Discovery of suppressors of CRMP2 phosphorylation reveals compounds that mimic the behavioral effects of lithium on amphetamine-induced hyperlocomotion.
Zhao WN, Tobe BTD, Udeshi ND, Xuan LL, Pernia CD, Zolg DP, Roberts AJ, Mani D, Blumenthal SR, Kurtser I, Patnaik D, Gaisina I, Bishop J, Sheridan SD, Lalonde J, Carr SA, Snyder EY, Haggarty SJ. Zhao WN, et al. Among authors: pernia cd. Transl Psychiatry. 2020 Feb 24;10(1):76. doi: 10.1038/s41398-020-0753-6. Transl Psychiatry. 2020. PMID: 32094324 Free PMC article.
A Biomarker for Predicting Responsiveness to Stem Cell Therapy Based on Mechanism-of-Action: Evidence from Cerebral Injury.
Hartman RE, Nathan NH, Ghosh N, Pernia CD, Law J, Nuryyev R, Plaia A, Yusof A, Tone B, Dulcich M, Wakeman DR, Dilmac N, Niles WD, Sidman RL, Obenaus A, Snyder EY, Ashwal S. Hartman RE, et al. Among authors: pernia cd. Cell Rep. 2020 May 12;31(6):107622. doi: 10.1016/j.celrep.2020.107622. Cell Rep. 2020. PMID: 32402283 Free article.
Circulating PACAP levels are associated with altered imaging measures of entorhinal cortex neurite density in posttraumatic stress disorder.
Granger SJ, May V, Hammack SE, Akman E, Jobson SA, Olson EA, Pernia CD, Daskalakis NP, Ravichandran C, Carlezon WA Jr, Ressler KJ, Rauch SL, Rosso IM. Granger SJ, et al. Among authors: pernia cd. Eur J Psychotraumatol. 2024;15(1):2335793. doi: 10.1080/20008066.2024.2335793. Epub 2024 Apr 8. Eur J Psychotraumatol. 2024. PMID: 38590134 Free PMC article.
Circulating PACAP levels are associated with altered imaging measures of entorhinal cortex neurite density in posttraumatic stress disorder.
Granger SJ, May V, Hammack SE, Akman E, Jobson SA, Olson EA, Pernia CD, Daskalakis NP, Ravichandran C, Carlezon WA, Ressler KJ, Rauch SL, Rosso IM. Granger SJ, et al. Among authors: pernia cd. medRxiv [Preprint]. 2023 Aug 31:2023.08.31.23294894. doi: 10.1101/2023.08.31.23294894. medRxiv. 2023. PMID: 37693514 Free PMC article. Updated. Preprint.
Single-Nucleus Transcriptome Profiling of Dorsolateral Prefrontal Cortex: Mechanistic Roles for Neuronal Gene Expression, Including the 17q21.31 Locus, in PTSD Stress Response.
Chatzinakos C, Pernia CD, Morrison FG, Iatrou A, McCullough KM, Schuler H, Snijders C, Bajaj T, DiPietro CP, Soliva Estruch M, Gassen NC, Anastasopoulos C, Bharadwaj RA, Bowlby BC, Hartmann J, Maihofer AX, Nievergelt CM, Ressler NM, Wolf EJ; Traumatic Stress Brain Research Group; PTSD BrainOmics Project of the PsychENCODE Consortium; PTSD Working Group of the Psychiatric Genomics Consortium; Carlezon WA Jr, Krystal JH, Kleinman JE, Girgenti MJ, Huber BR, Kellis M, Logue MW, Miller MW, Ressler KJ, Daskalakis NP. Chatzinakos C, et al. Among authors: pernia cd. Am J Psychiatry. 2023 Oct 1;180(10):739-754. doi: 10.1176/appi.ajp.20220478. Epub 2023 Jul 26. Am J Psychiatry. 2023. PMID: 37491937
12 results