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Comprehensive characterization of the prostate tumor microenvironment identifies CXCR4/CXCL12 crosstalk as a novel antiangiogenic therapeutic target in prostate cancer.
Heidegger I, Fotakis G, Offermann A, Goveia J, Daum S, Salcher S, Noureen A, Timmer-Bosscha H, Schäfer G, Walenkamp A, Perner S, Beatovic A, Moisse M, Plattner C, Krogsdam A, Haybaeck J, Sopper S, Thaler S, Keller MA, Klocker H, Trajanoski Z, Wolf D, Pircher A. Heidegger I, et al. Among authors: perner s. Mol Cancer. 2022 Jun 18;21(1):132. doi: 10.1186/s12943-022-01597-7. Mol Cancer. 2022. PMID: 35717322 Free PMC article.
MED15, encoding a subunit of the mediator complex, is overexpressed at high frequency in castration-resistant prostate cancer.
Adler D, Menon R, Braun M, Offermann A, Queisser A, Boehm D, Vogel W, Rüenauver K, Ruiz C, Zellweger T, Svensson M, Andren O, Kristiansen G, Wernert N, Bubendorf L, Kirfel J, Biskup S, Perner S. Adler D, et al. Among authors: perner s. Int J Cancer. 2014 Jul 1;135(1):19-26. doi: 10.1002/ijc.28647. Epub 2013 Dec 9. Int J Cancer. 2014. PMID: 24374838 Free article.
MED12 overexpression is a frequent event in castration-resistant prostate cancer.
Adler D, Offermann A, Braun M, Menon R, Syring I, Nowak M, Halbach R, Vogel W, Ruiz C, Zellweger T, Rentsch CA, Svensson M, Andren O, Bubendorf L, Biskup S, Duensing S, Kirfel J, Perner S. Adler D, et al. Among authors: perner s. Endocr Relat Cancer. 2014 Aug;21(4):663-675. doi: 10.1530/ERC-14-0171. Epub 2014 Jun 17. Endocr Relat Cancer. 2014. PMID: 24938407
Clinical and molecular implications of MED15 in head and neck squamous cell carcinoma.
Adler D, Offermann A, Halbach R, Vogel W, Braun M, Kristiansen G, Bootz F, Wenzel J, Mikut R, Lengerke C, Reischl M, Schröck A, Perner S. Adler D, et al. Among authors: perner s. Am J Pathol. 2015 Apr;185(4):1114-22. doi: 10.1016/j.ajpath.2014.12.010. Epub 2015 Mar 16. Am J Pathol. 2015. PMID: 25791637 Free article.
Comprehensive analysis of the transcriptional profile of the Mediator complex across human cancer types.
Syring I, Klümper N, Offermann A, Braun M, Deng M, Boehm D, Queisser A, von Mässenhausen A, Brägelmann J, Vogel W, Schmidt D, Majores M, Schindler A, Kristiansen G, Müller SC, Ellinger J, Adler D, Perner S. Syring I, et al. Among authors: perner s. Oncotarget. 2016 Apr 26;7(17):23043-23055. doi: 10.18632/oncotarget.8469. Oncotarget. 2016. PMID: 27050271 Free PMC article.
320 results