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A Novel Role for the Tumor Suppressor Gene ITF2 in Tumorigenesis and Chemotherapy Response.
Pernía O, Sastre-Perona A, Rodriguez-Antolín C, García-Guede A, Palomares-Bralo M, Rosas R, Sanchez-Cabrero D, Cruz P, Rodriguez C, Diestro M, Martín-Arenas R, Pulido V, Santisteban P, Castro J, Vera O, Ibáñez de Cáceres I. Pernía O, et al. Cancers (Basel). 2020 Mar 26;12(4):786. doi: 10.3390/cancers12040786. Cancers (Basel). 2020. PMID: 32224864 Free PMC article.
IGFBP-3 methylation-derived deficiency mediates the resistance to cisplatin through the activation of the IGFIR/Akt pathway in non-small cell lung cancer.
Cortés-Sempere M, de Miguel MP, Pernía O, Rodriguez C, de Castro Carpeño J, Nistal M, Conde E, López-Ríos F, Belda-Iniesta C, Perona R, Ibanez de Caceres I. Cortés-Sempere M, et al. Among authors: pernia o. Oncogene. 2013 Mar 7;32(10):1274-83. doi: 10.1038/onc.2012.146. Epub 2012 Apr 30. Oncogene. 2013. PMID: 22543588
DNA Methylation of miR-7 is a Mechanism Involved in Platinum Response through MAFG Overexpression in Cancer Cells.
Vera O, Jimenez J, Pernia O, Rodriguez-Antolin C, Rodriguez C, Sanchez Cabo F, Soto J, Rosas R, Lopez-Magallon S, Esteban Rodriguez I, Dopazo A, Rojo F, Belda C, Alvarez R, Valentin J, Benitez J, Perona R, De Castro J, Ibanez de Caceres I. Vera O, et al. Among authors: pernia o. Theranostics. 2017 Sep 22;7(17):4118-4134. doi: 10.7150/thno.20112. eCollection 2017. Theranostics. 2017. PMID: 29158814 Free PMC article.
High expression of MKP1/DUSP1 counteracts glioma stem cell activity and mediates HDAC inhibitor response.
Arrizabalaga O, Moreno-Cugnon L, Auzmendi-Iriarte J, Aldaz P, Ibanez de Caceres I, Garros-Regulez L, Moncho-Amor V, Torres-Bayona S, Pernía O, Pintado-Berninches L, Carrasco-Ramirez P, Cortes-Sempere M, Rosas R, Sanchez-Gomez P, Ruiz I, Caren H, Pollard S, Garcia I, Sacido AA, Lovell-Badge R, Belda-Iniesta C, Sampron N, Perona R, Matheu A. Arrizabalaga O, et al. Among authors: pernia o. Oncogenesis. 2017 Dec 14;6(12):401. doi: 10.1038/s41389-017-0003-9. Oncogenesis. 2017. PMID: 29284798 Free PMC article.
MAFG is a potential therapeutic target to restore chemosensitivity in cisplatin-resistant cancer cells by increasing reactive oxygen species.
Vera-Puente O, Rodriguez-Antolin C, Salgado-Figueroa A, Michalska P, Pernia O, Reid BM, Rosas R, Garcia-Guede A, SacristÁn S, Jimenez J, Esteban-Rodriguez I, Martin ME, Sellers TA, León R, Gonzalez VM, De Castro J, Ibanez de Caceres I. Vera-Puente O, et al. Among authors: pernia o. Transl Res. 2018 Oct;200:1-17. doi: 10.1016/j.trsl.2018.06.005. Epub 2018 Jun 30. Transl Res. 2018. PMID: 30053382 Free PMC article.
Functional analysis of new variants at the low-density lipoprotein receptor associated with familial hypercholesterolemia.
Rodríguez-Jiménez C, Pernía O, Mostaza J, Rodríguez-Antolín C, de Dios García-Díaz J, Alonso-Cerezo C, García-Polo I, Blanco A, Lahoz C, Arrieta F, Beltrán L, Díaz de Bustamante A, Garzón-Lorenzo L, Álvarez-Sala LA, Asenjo Á, Ibáñez de Cáceres I, Rodríguez-Nóvoa S. Rodríguez-Jiménez C, et al. Among authors: pernia o. Hum Mutat. 2019 Aug;40(8):1181-1190. doi: 10.1002/humu.23801. Epub 2019 Jun 18. Hum Mutat. 2019. PMID: 31106925
Hypermethylation of Anti-oncogenic MicroRNA 7 is Increased in Emphysema Patients.
Rosas-Alonso R, Galera R, Sánchez-Pascuala JJ, Casitas R, Burdiel M, Martínez-Cerón E, Vera O, Rodriguez-Antolin C, Pernía O, De Castro J, García-Rio F, Ibanez-de-Cáceres I. Rosas-Alonso R, et al. Among authors: pernia o. Arch Bronconeumol (Engl Ed). 2020 Aug;56(8):506-513. doi: 10.1016/j.arbres.2019.10.017. Epub 2019 Nov 25. Arch Bronconeumol (Engl Ed). 2020. PMID: 31780284 English, Spanish.
26 results