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Single-nucleus transcriptomics of the prefrontal cortex in major depressive disorder implicates oligodendrocyte precursor cells and excitatory neurons.
Nagy C, Maitra M, Tanti A, Suderman M, Théroux JF, Davoli MA, Perlman K, Yerko V, Wang YC, Tripathy SJ, Pavlidis P, Mechawar N, Ragoussis J, Turecki G. Nagy C, et al. Among authors: perlman k. Nat Neurosci. 2020 Jun;23(6):771-781. doi: 10.1038/s41593-020-0621-y. Epub 2020 Apr 27. Nat Neurosci. 2020. PMID: 32341540
Child abuse associates with increased recruitment of perineuronal nets in the ventromedial prefrontal cortex: a possible implication of oligodendrocyte progenitor cells.
Tanti A, Belliveau C, Nagy C, Maitra M, Denux F, Perlman K, Chen F, Mpai R, Canonne C, Théberge S, McFarquhar A, Davoli MA, Belzung C, Turecki G, Mechawar N. Tanti A, et al. Among authors: perlman k. Mol Psychiatry. 2022 Mar;27(3):1552-1561. doi: 10.1038/s41380-021-01372-y. Epub 2021 Nov 19. Mol Psychiatry. 2022. PMID: 34799691 Free PMC article.
Evaluating the perceived utility of an artificial intelligence-powered clinical decision support system for depression treatment using a simulation center.
Tanguay-Sela M, Benrimoh D, Popescu C, Perez T, Rollins C, Snook E, Lundrigan E, Armstrong C, Perlman K, Fratila R, Mehltretter J, Israel S, Champagne M, Williams J, Simard J, Parikh SV, Karp JF, Heller K, Linnaranta O, Cardona LG, Turecki G, Margolese HC. Tanguay-Sela M, et al. Among authors: perlman k. Psychiatry Res. 2022 Feb;308:114336. doi: 10.1016/j.psychres.2021.114336. Epub 2021 Dec 11. Psychiatry Res. 2022. PMID: 34953204
Cell type specific transcriptomic differences in depression show similar patterns between males and females but implicate distinct cell types and genes.
Maitra M, Mitsuhashi H, Rahimian R, Chawla A, Yang J, Fiori LM, Davoli MA, Perlman K, Aouabed Z, Mash DC, Suderman M, Mechawar N, Turecki G, Nagy C. Maitra M, et al. Among authors: perlman k. Nat Commun. 2023 May 22;14(1):2912. doi: 10.1038/s41467-023-38530-5. Nat Commun. 2023. PMID: 37217515 Free PMC article.
108 results