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Discovery of a Highly Selective Glycogen Synthase Kinase-3 Inhibitor (PF-04802367) That Modulates Tau Phosphorylation in the Brain: Translation for PET Neuroimaging.
Liang SH, Chen JM, Normandin MD, Chang JS, Chang GC, Taylor CK, Trapa P, Plummer MS, Para KS, Conn EL, Lopresti-Morrow L, Lanyon LF, Cook JM, Richter KE, Nolan CE, Schachter JB, Janat F, Che Y, Shanmugasundaram V, Lefker BA, Enerson BE, Livni E, Wang L, Guehl NJ, Patnaik D, Wagner FF, Perlis R, Holson EB, Haggarty SJ, El Fakhri G, Kurumbail RG, Vasdev N. Liang SH, et al. Among authors: perlis r. Angew Chem Int Ed Engl. 2016 Aug 8;55(33):9601-5. doi: 10.1002/anie.201603797. Epub 2016 Jun 29. Angew Chem Int Ed Engl. 2016. PMID: 27355874 Free PMC article.
Epigenetic mechanisms in mood disorders: targeting neuroplasticity.
Fass DM, Schroeder FA, Perlis RH, Haggarty SJ. Fass DM, et al. Among authors: perlis rh. Neuroscience. 2014 Apr 4;264:112-30. doi: 10.1016/j.neuroscience.2013.01.041. Epub 2013 Jan 30. Neuroscience. 2014. PMID: 23376737 Free PMC article. Review.
Characterization of bipolar disorder patient-specific induced pluripotent stem cells from a family reveals neurodevelopmental and mRNA expression abnormalities.
Madison JM, Zhou F, Nigam A, Hussain A, Barker DD, Nehme R, van der Ven K, Hsu J, Wolf P, Fleishman M, O'Dushlaine C, Rose S, Chambert K, Lau FH, Ahfeldt T, Rueckert EH, Sheridan SD, Fass DM, Nemesh J, Mullen TE, Daheron L, McCarroll S, Sklar P, Perlis RH, Haggarty SJ. Madison JM, et al. Among authors: perlis rh. Mol Psychiatry. 2015 Jun;20(6):703-17. doi: 10.1038/mp.2015.7. Epub 2015 Mar 3. Mol Psychiatry. 2015. PMID: 25733313 Free PMC article.
PET neuroimaging reveals histone deacetylase dysregulation in schizophrenia.
Gilbert TM, Zürcher NR, Wu CJ, Bhanot A, Hightower BG, Kim M, Albrecht DS, Wey HY, Schroeder FA, Rodriguez-Thompson A, Morin TM, Hart KL, Pellegrini AM, Riley MM, Wang C, Stufflebeam SM, Haggarty SJ, Holt DJ, Loggia ML, Perlis RH, Brown HE, Roffman JL, Hooker JM. Gilbert TM, et al. Among authors: perlis rh. J Clin Invest. 2019 Jan 2;129(1):364-372. doi: 10.1172/JCI123743. Epub 2018 Dec 10. J Clin Invest. 2019. PMID: 30530989 Free PMC article. Clinical Trial.
440 results