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Video-based valve motion combined with computational fluid dynamics gives stable and accurate simulations of blood flow in the Realheart total artificial heart.
Artif Organs. 2022 Jan;46(1):57-70. doi: 10.1111/aor.14056. Epub 2021 Sep 20.
Artif Organs. 2022.
PMID: 34460941
Hemodilution Increases the Susceptibility of Red Blood Cells to Mechanical Shear Stress During In Vitro Hemolysis Testing.
Sargent CR, Perkins IL, Kanamarlapudi V, Moriarty C, Ali S.
Sargent CR, et al. Among authors: perkins il.
ASAIO J. 2021 Jun 1;67(6):632-641. doi: 10.1097/MAT.0000000000001280.
ASAIO J. 2021.
PMID: 32947284
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Hemodynamic characterization of the Realheart® total artificial heart with a hybrid cardiovascular simulator.
Fresiello L, Najar A, Brynedal Ignell N, Zieliński K, Rocchi M, Meyns B, Perkins IL.
Fresiello L, et al. Among authors: perkins il.
Artif Organs. 2022 Aug;46(8):1585-1596. doi: 10.1111/aor.14223. Epub 2022 Mar 27.
Artif Organs. 2022.
PMID: 35231138
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In vitro hemolytic performance of the Realheart® V11C TAH prototype with porcine blood.
Perkins IL, Mansisidor EM, Zaman SF, Mudge K, Bodger O, Najar A.
Perkins IL, et al.
Artif Organs. 2023 Jul;47(7):1208-1213. doi: 10.1111/aor.14533. Epub 2023 Apr 27.
Artif Organs. 2023.
PMID: 37032479
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Fluid-structure interaction modelling of a positive-displacement Total Artificial Heart.
Bornoff J, Najar A, Fresiello L, Finocchiaro T, Perkins IL, Gill H, Cookson AN, Fraser KH.
Bornoff J, et al. Among authors: perkins il.
Sci Rep. 2023 Apr 14;13(1):5734. doi: 10.1038/s41598-023-32141-2.
Sci Rep. 2023.
PMID: 37059748
Free PMC article.
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Overset meshing in combination with novel blended weak-strong fluid-structure interactions for simulations of a translating valve in series with a second valve.
Bornoff J, Gill HS, Najar A, Perkins IL, Cookson AN, Fraser KH.
Bornoff J, et al. Among authors: perkins il.
Comput Methods Biomech Biomed Engin. 2024 May;27(6):736-750. doi: 10.1080/10255842.2023.2199903. Epub 2023 Apr 18.
Comput Methods Biomech Biomed Engin. 2024.
PMID: 37071538
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Preclinical Device Thrombogenicity Assessments: Key Messages From the 2018 FDA, Industry, and Academia Forum.
Jamiolkowski MA, Snyder TA, Perkins IL, Malinauskas RA, Lu Q.
Jamiolkowski MA, et al. Among authors: perkins il.
ASAIO J. 2021 Feb 1;67(2):214-219. doi: 10.1097/MAT.0000000000001226.
ASAIO J. 2021.
PMID: 33512917
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