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507 results

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Page 1
Landiolol and Organ Failure in Patients With Septic Shock: The STRESS-L Randomized Clinical Trial.
Whitehouse T, Hossain A, Perkins GD, Gordon AC, Bion J, Young D, McAuley D, Singer M, Lord J, Gates S, Veenith T, MacCallum NS, Yeung J, Innes R, Welters I, Boota N, Skilton E, Ghuman B, Hill M, Regan SE, Mistry D, Lall R; STRESS-L Collaborators. Whitehouse T, et al. Among authors: perkins gd. JAMA. 2023 Nov 7;330(17):1641-1652. doi: 10.1001/jama.2023.20134. JAMA. 2023. PMID: 37877587 Free PMC article.
Effect of intravenous β-2 agonist treatment on clinical outcomes in acute respiratory distress syndrome (BALTI-2): a multicentre, randomised controlled trial.
Gao Smith F, Perkins GD, Gates S, Young D, McAuley DF, Tunnicliffe W, Khan Z, Lamb SE; BALTI-2 study investigators. Gao Smith F, et al. Among authors: perkins gd. Lancet. 2012 Jan 21;379(9812):229-35. doi: 10.1016/S0140-6736(11)61623-1. Epub 2011 Dec 11. Lancet. 2012. PMID: 22166903 Free PMC article. Clinical Trial.
Airway pressure release ventilation: a survey of UK practice.
Rose L, Camporota L, Mills GH, Laffey J, Perkins GD, Shankar-Hari M, Szakmany T, McAuley D; RELEASE investigators. Rose L, et al. Among authors: perkins gd. Br J Anaesth. 2023 Jan;130(1):e25-e27. doi: 10.1016/j.bja.2022.10.017. Epub 2022 Nov 23. Br J Anaesth. 2023. PMID: 36435668 Free article. No abstract available.
Role of immunosuppression in an antibiotic stewardship intervention and its association with clinical outcomes and antibiotic use: protocol for an observational study (RISC-sepsis).
Scott J, Trevi L, McNeil H, Ewen T, Mawson P, McDonald D, Filby A, Lall R, Booth K, Boschman G, Melkebeek V, Perkins G, McMullan R, McAuley DF, McCullagh IJ, Walsh T, Rostron A, Shankar-Hari M, Dark P, Simpson AJ, Conway Morris A, Hellyer TP. Scott J, et al. BMJ Open. 2022 Dec 9;12(12):e068321. doi: 10.1136/bmjopen-2022-068321. BMJ Open. 2022. PMID: 36600326 Free PMC article.
"Sugar or Salt" (SOS) trial protocol summary.
Rowland MJ, Veenith T, Scomparin C, Wilson MH, Hutchinson PJ, Kolias A, Lall R, Regan S, Mason J, Andrews PJD, Horner D, Naisbitt J, Devrell A, Malins A, Dark P, McAuley D, Perkins GD. Rowland MJ, et al. Among authors: perkins gd. J Intensive Care Soc. 2022 Nov;23(4):492. doi: 10.1177/17511437211035515. Epub 2021 Oct 28. J Intensive Care Soc. 2022. PMID: 36751348 Free PMC article. No abstract available.
Repair of Acute Respiratory Distress Syndrome in COVID-19 by Stromal Cells (REALIST-COVID Trial): A Multicenter, Randomized, Controlled Clinical Trial.
Gorman EA, Rynne J, Gardiner HJ, Rostron AJ, Bannard-Smith J, Bentley AM, Brealey D, Campbell C, Curley G, Clarke M, Dushianthan A, Hopkins P, Jackson C, Kefela K, Krasnodembskaya A, Laffey JG, McDowell C, McFarland M, McFerran J, McGuigan P, Perkins GD, Silversides J, Smythe J, Thompson J, Tunnicliffe WS, Welters IDM, Amado-Rodríguez L, Albaiceta G, Williams B, Shankar-Hari M, McAuley DF, O'Kane CM. Gorman EA, et al. Among authors: perkins gd. Am J Respir Crit Care Med. 2023 Aug 1;208(3):256-269. doi: 10.1164/rccm.202302-0297OC. Am J Respir Crit Care Med. 2023. PMID: 37154608 Clinical Trial.
biomArker-guided Duration of Antibiotic treatment in hospitalised Patients with suspecTed Sepsis (ADAPT-Sepsis): A protocol for a multicentre randomised controlled trial.
Dark P, Perkins GD, McMullan R, McAuley D, Gordon AC, Clayton J, Mistry D, Young K, Regan S, McGowan N, Stevenson M, Gates S, Carlson GL, Walsh T, Lone NI, Mouncey PR, Singer M, Wilson P, Felton T, Marshall K, Hossain AM, Lall R. Dark P, et al. Among authors: perkins gd. J Intensive Care Soc. 2023 Nov;24(4):427-434. doi: 10.1177/17511437231169193. Epub 2023 Apr 25. J Intensive Care Soc. 2023. PMID: 37841304 Free PMC article.
Impaired alveolar macrophage 11β-hydroxysteroid dehydrogenase type 1 reductase activity contributes to increased pulmonary inflammation and mortality in sepsis-related ARDS.
Mahida RY, Lax S, Bassford CR, Scott A, Parekh D, Hardy RS, Naidu B, Matthay MA, Stewart PM, Cooper MC, Perkins GD, Thickett DR. Mahida RY, et al. Among authors: perkins gd. Front Immunol. 2023 Apr 27;14:1159831. doi: 10.3389/fimmu.2023.1159831. eCollection 2023. Front Immunol. 2023. PMID: 37180160 Free PMC article.
The SWiFT trial (Study of Whole Blood in Frontline Trauma)-the clinical and cost effectiveness of pre-hospital whole blood versus standard care in patients with life-threatening traumatic haemorrhage: study protocol for a multi-centre randomised controlled trial.
Smith JE, Barnard EBG, Brown-O'Sullivan C, Cardigan R, Davies J, Hawton A, Laing E, Lucas J, Lyon R, Perkins GD, Smith L, Stanworth SJ, Weaver A, Woolley T, Green L. Smith JE, et al. Among authors: perkins gd. Trials. 2023 Nov 14;24(1):725. doi: 10.1186/s13063-023-07711-4. Trials. 2023. PMID: 37964393 Free PMC article.
Alpha 2 agonists for sedation to produce better outcomes from critical illness (A2B Trial): protocol for a multicentre phase 3 pragmatic clinical and cost-effectiveness randomised trial in the UK.
Walsh TS, Aitken LM, McKenzie CA, Boyd J, Macdonald A, Giddings A, Hope D, Norrie J, Weir C, Parker RA, Lone NI, Emerson L, Kydonaki K, Creagh-Brown B, Morris S, McAuley DF, Dark P, Wise MP, Gordon AC, Perkins G, Reade M, Blackwood B, MacLullich A, Glen R, Page VJ. Walsh TS, et al. BMJ Open. 2023 Dec 10;13(12):e078645. doi: 10.1136/bmjopen-2023-078645. BMJ Open. 2023. PMID: 38072483 Free PMC article.
507 results