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Dynamic allostery governs cyclophilin A-HIV capsid interplay.
Lu M, Hou G, Zhang H, Suiter CL, Ahn J, Byeon IJ, Perilla JR, Langmead CJ, Hung I, Gor'kov PL, Gan Z, Brey W, Aiken C, Zhang P, Schulten K, Gronenborn AM, Polenova T. Lu M, et al. Among authors: perilla jr. Proc Natl Acad Sci U S A. 2015 Nov 24;112(47):14617-22. doi: 10.1073/pnas.1516920112. Epub 2015 Nov 9. Proc Natl Acad Sci U S A. 2015. PMID: 26553990 Free PMC article.
Cyclophilin A stabilizes the HIV-1 capsid through a novel non-canonical binding site.
Liu C, Perilla JR, Ning J, Lu M, Hou G, Ramalho R, Himes BA, Zhao G, Bedwell GJ, Byeon IJ, Ahn J, Gronenborn AM, Prevelige PE, Rousso I, Aiken C, Polenova T, Schulten K, Zhang P. Liu C, et al. Among authors: perilla jr. Nat Commun. 2016 Mar 4;7:10714. doi: 10.1038/ncomms10714. Nat Commun. 2016. PMID: 26940118 Free PMC article.
Quenching protein dynamics interferes with HIV capsid maturation.
Wang M, Quinn CM, Perilla JR, Zhang H, Shirra R Jr, Hou G, Byeon IJ, Suiter CL, Ablan S, Urano E, Nitz TJ, Aiken C, Freed EO, Zhang P, Schulten K, Gronenborn AM, Polenova T. Wang M, et al. Among authors: perilla jr. Nat Commun. 2017 Nov 24;8(1):1779. doi: 10.1038/s41467-017-01856-y. Nat Commun. 2017. PMID: 29176596 Free PMC article.
58 results