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Structural basis of HIV-1 maturation inhibitor binding and activity.
Sarkar S, Zadrozny KK, Zadorozhnyi R, Russell RW, Quinn CM, Kleinpeter A, Ablan S, Meshkin H, Perilla JR, Freed EO, Ganser-Pornillos BK, Pornillos O, Gronenborn AM, Polenova T. Sarkar S, et al. Among authors: perilla jr. Nat Commun. 2023 Mar 4;14(1):1237. doi: 10.1038/s41467-023-36569-y. Nat Commun. 2023. PMID: 36871077 Free PMC article.
Molecular dynamics simulations of large macromolecular complexes.
Perilla JR, Goh BC, Cassidy CK, Liu B, Bernardi RC, Rudack T, Yu H, Wu Z, Schulten K. Perilla JR, et al. Curr Opin Struct Biol. 2015 Apr;31:64-74. doi: 10.1016/j.sbi.2015.03.007. Epub 2015 Apr 4. Curr Opin Struct Biol. 2015. PMID: 25845770 Free PMC article. Review.
Dynamic allostery governs cyclophilin A-HIV capsid interplay.
Lu M, Hou G, Zhang H, Suiter CL, Ahn J, Byeon IJ, Perilla JR, Langmead CJ, Hung I, Gor'kov PL, Gan Z, Brey W, Aiken C, Zhang P, Schulten K, Gronenborn AM, Polenova T. Lu M, et al. Among authors: perilla jr. Proc Natl Acad Sci U S A. 2015 Nov 24;112(47):14617-22. doi: 10.1073/pnas.1516920112. Epub 2015 Nov 9. Proc Natl Acad Sci U S A. 2015. PMID: 26553990 Free PMC article.
Cyclophilin A stabilizes the HIV-1 capsid through a novel non-canonical binding site.
Liu C, Perilla JR, Ning J, Lu M, Hou G, Ramalho R, Himes BA, Zhao G, Bedwell GJ, Byeon IJ, Ahn J, Gronenborn AM, Prevelige PE, Rousso I, Aiken C, Polenova T, Schulten K, Zhang P. Liu C, et al. Among authors: perilla jr. Nat Commun. 2016 Mar 4;7:10714. doi: 10.1038/ncomms10714. Nat Commun. 2016. PMID: 26940118 Free PMC article.
Molecular Architecture of the Retroviral Capsid.
Perilla JR, Gronenborn AM. Perilla JR, et al. Trends Biochem Sci. 2016 May;41(5):410-420. doi: 10.1016/j.tibs.2016.02.009. Epub 2016 Mar 30. Trends Biochem Sci. 2016. PMID: 27039020 Free PMC article. Review.
58 results