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Inositol phosphates are assembly co-factors for HIV-1.
Dick RA, Zadrozny KK, Xu C, Schur FKM, Lyddon TD, Ricana CL, Wagner JM, Perilla JR, Ganser-Pornillos BK, Johnson MC, Pornillos O, Vogt VM. Dick RA, et al. Among authors: perilla jr. Nature. 2018 Aug;560(7719):509-512. doi: 10.1038/s41586-018-0396-4. Epub 2018 Aug 1. Nature. 2018. PMID: 30069050 Free PMC article.
Cyclophilin A stabilizes the HIV-1 capsid through a novel non-canonical binding site.
Liu C, Perilla JR, Ning J, Lu M, Hou G, Ramalho R, Himes BA, Zhao G, Bedwell GJ, Byeon IJ, Ahn J, Gronenborn AM, Prevelige PE, Rousso I, Aiken C, Polenova T, Schulten K, Zhang P. Liu C, et al. Among authors: perilla jr. Nat Commun. 2016 Mar 4;7:10714. doi: 10.1038/ncomms10714. Nat Commun. 2016. PMID: 26940118 Free PMC article.
Quenching protein dynamics interferes with HIV capsid maturation.
Wang M, Quinn CM, Perilla JR, Zhang H, Shirra R Jr, Hou G, Byeon IJ, Suiter CL, Ablan S, Urano E, Nitz TJ, Aiken C, Freed EO, Zhang P, Schulten K, Gronenborn AM, Polenova T. Wang M, et al. Among authors: perilla jr. Nat Commun. 2017 Nov 24;8(1):1779. doi: 10.1038/s41467-017-01856-y. Nat Commun. 2017. PMID: 29176596 Free PMC article.
Author Correction: Inositol phosphates are assembly co-factors for HIV-1.
Dick RA, Zadrozny KK, Xu C, Schur FKM, Lyddon TD, Ricana CL, Wagner JM, Perilla JR, Ganser-Pornillos BK, Johnson MC, Pornillos O, Vogt VM. Dick RA, et al. Among authors: perilla jr. Nature. 2018 Nov;563(7731):E22. doi: 10.1038/s41586-018-0505-4. Nature. 2018. PMID: 30158708
Dynamic regulation of HIV-1 capsid interaction with the restriction factor TRIM5α identified by magic-angle spinning NMR and molecular dynamics simulations.
Quinn CM, Wang M, Fritz MP, Runge B, Ahn J, Xu C, Perilla JR, Gronenborn AM, Polenova T. Quinn CM, et al. Among authors: perilla jr. Proc Natl Acad Sci U S A. 2018 Nov 6;115(45):11519-11524. doi: 10.1073/pnas.1800796115. Epub 2018 Oct 17. Proc Natl Acad Sci U S A. 2018. PMID: 30333189 Free PMC article.
58 results