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A Multistage Formulation Based on Full-Length CSP and AMA-1 Ectodomain of Plasmodium vivax Induces High Antibody Titers and T-cells and Partially Protects Mice Challenged with a Transgenic Plasmodium berghei Parasite.
Lima LC, Marques RF, Gimenez AM, Françoso KS, Aliprandini E, Camargo TM, Aguiar ACC, Pereira DB, Renia L, Amino R, Soares IS. Lima LC, et al. Among authors: pereira db. Microorganisms. 2020 Jun 17;8(6):916. doi: 10.3390/microorganisms8060916. Microorganisms. 2020. PMID: 32560380 Free PMC article.
T follicular helper cells regulate the activation of B lymphocytes and antibody production during Plasmodium vivax infection.
Figueiredo MM, Costa PAC, Diniz SQ, Henriques PM, Kano FS, Tada MS, Pereira DB, Soares IS, Martins-Filho OA, Jankovic D, Gazzinelli RT, Antonelli LRDV. Figueiredo MM, et al. Among authors: pereira db. PLoS Pathog. 2017 Jul 10;13(7):e1006484. doi: 10.1371/journal.ppat.1006484. eCollection 2017 Jul. PLoS Pathog. 2017. PMID: 28700710 Free PMC article.
Potent Antimalarials with Development Potential Identified by Structure-Guided Computational Optimization of a Pyrrole-Based Dihydroorotate Dehydrogenase Inhibitor Series.
Palmer MJ, Deng X, Watts S, Krilov G, Gerasyuto A, Kokkonda S, El Mazouni F, White J, White KL, Striepen J, Bath J, Schindler KA, Yeo T, Shackleford DM, Mok S, Deni I, Lawong A, Huang A, Chen G, Wang W, Jayaseelan J, Katneni K, Patil R, Saunders J, Shahi SP, Chittimalla R, Angulo-Barturen I, Jiménez-Díaz MB, Wittlin S, Tumwebaze PK, Rosenthal PJ, Cooper RA, Aguiar ACC, Guido RVC, Pereira DB, Mittal N, Winzeler EA, Tomchick DR, Laleu B, Burrows JN, Rathod PK, Fidock DA, Charman SA, Phillips MA. Palmer MJ, et al. Among authors: pereira db. J Med Chem. 2021 May 13;64(9):6085-6136. doi: 10.1021/acs.jmedchem.1c00173. Epub 2021 Apr 20. J Med Chem. 2021. PMID: 33876936 Free PMC article.
Repositioning and Characterization of 1-(Pyridin-4-yl)pyrrolidin-2-one Derivatives as Plasmodium Cytoplasmic Prolyl-tRNA Synthetase Inhibitors.
Okaniwa M, Shibata A, Ochida A, Akao Y, White KL, Shackleford DM, Duffy S, Lucantoni L, Dey S, Striepen J, Yeo T, Mok S, Aguiar ACC, Sturm A, Crespo B, Sanz LM, Churchyard A, Baum J, Pereira DB, Guido RVC, Dechering KJ, Wittlin S, Uhlemann AC, Fidock DA, Niles JC, Avery VM, Charman SA, Laleu B. Okaniwa M, et al. Among authors: pereira db. ACS Infect Dis. 2021 Jun 11;7(6):1680-1689. doi: 10.1021/acsinfecdis.1c00020. Epub 2021 Apr 30. ACS Infect Dis. 2021. PMID: 33929818 Free PMC article.
Distinctive genetic structure and selection patterns in Plasmodium vivax from South Asia and East Africa.
Benavente ED, Manko E, Phelan J, Campos M, Nolder D, Fernandez D, Velez-Tobon G, Castaño AT, Dombrowski JG, Marinho CRF, Aguiar ACC, Pereira DB, Sriprawat K, Nosten F, Moon R, Sutherland CJ, Campino S, Clark TG. Benavente ED, et al. Among authors: pereira db. Nat Commun. 2021 May 26;12(1):3160. doi: 10.1038/s41467-021-23422-3. Nat Commun. 2021. PMID: 34039976 Free PMC article.
A Comprehensive Analysis of the Genetic Diversity of Plasmodium falciparum Histidine-Rich Protein 2 (PfHRP2) in the Brazilian Amazon.
Costa GL, Mascarenhas MEP, Martin TOG, Fortini LG, Louzada J, Pereira DB, Aguiar ACC, Carvalho LH, de Brito CFA, Fontes CJF, de Sousa TN. Costa GL, et al. Among authors: pereira db. Front Cell Infect Microbiol. 2021 Sep 21;11:742681. doi: 10.3389/fcimb.2021.742681. eCollection 2021. Front Cell Infect Microbiol. 2021. PMID: 34621693 Free PMC article.
Population-based genomic study of Plasmodium vivax malaria in seven Brazilian states and across South America.
Ibrahim A, Manko E, Dombrowski JG, Campos M, Benavente ED, Nolder D, Sutherland CJ, Nosten F, Fernandez D, Vélez-Tobón G, Castaño AT, Aguiar ACC, Pereira DB, da Silva Santos S, Suarez-Mutis M, Di Santi SM, Regina de Souza Baptista A, Dantas Machado RL, Marinho CRF, Clark TG, Campino S. Ibrahim A, et al. Among authors: pereira db. Lancet Reg Health Am. 2023 Jan 2;18:100420. doi: 10.1016/j.lana.2022.100420. eCollection 2023 Feb. Lancet Reg Health Am. 2023. PMID: 36844008 Free PMC article.
124 results