Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

Search Results

23 results

Filters applied: . Clear all
Results are displayed in a computed author sort order. The Results By Year timeline is not available.
Page 1
Chemical modulation of microtubule structure through the laulimalide/peloruside site.
Estévez-Gallego J, Álvarez-Bernad B, Pera B, Wullschleger C, Raes O, Menche D, Martínez JC, Lucena-Agell D, Prota AE, Bonato F, Bargsten K, Cornelus J, Giménez-Abián JF, Northcote P, Steinmetz MO, Kamimura S, Altmann KH, Paterson I, Gago F, Van der Eycken J, Díaz JF, Oliva MÁ. Estévez-Gallego J, et al. Among authors: pera b. Structure. 2023 Jan 5;31(1):88-99.e5. doi: 10.1016/j.str.2022.11.006. Epub 2022 Dec 2. Structure. 2023. PMID: 36462501 Free article.
Zampanolide, a potent new microtubule-stabilizing agent, covalently reacts with the taxane luminal site in tubulin α,β-heterodimers and microtubules.
Field JJ, Pera B, Calvo E, Canales A, Zurwerra D, Trigili C, Rodríguez-Salarichs J, Matesanz R, Kanakkanthara A, Wakefield SJ, Singh AJ, Jiménez-Barbero J, Northcote P, Miller JH, López JA, Hamel E, Barasoain I, Altmann KH, Díaz JF. Field JJ, et al. Among authors: pera b. Chem Biol. 2012 Jun 22;19(6):686-98. doi: 10.1016/j.chembiol.2012.05.008. Chem Biol. 2012. PMID: 22726683 Free PMC article.
Modulation of microtubule interprotofilament interactions by modified taxanes.
Matesanz R, Rodríguez-Salarichs J, Pera B, Canales A, Andreu JM, Jiménez-Barbero J, Bras W, Nogales A, Fang WS, Díaz JF. Matesanz R, et al. Among authors: pera b. Biophys J. 2011 Dec 21;101(12):2970-80. doi: 10.1016/j.bpj.2011.11.005. Epub 2011 Dec 20. Biophys J. 2011. PMID: 22208196 Free PMC article.
A structure-based design of new C2- and C13-substituted taxanes: tubulin binding affinities and extended quantitative structure-activity relationships using comparative binding energy (COMBINE) analysis.
Coderch C, Tang Y, Klett J, Zhang SE, Ma YT, Shaorong W, Matesanz R, Pera B, Canales A, Jiménez-Barbero J, Morreale A, Díaz JF, Fang WS, Gago F. Coderch C, et al. Among authors: pera b. Org Biomol Chem. 2013 May 14;11(18):3046-56. doi: 10.1039/c3ob40407b. Org Biomol Chem. 2013. PMID: 23532250 Free article.
Taxanes with high potency inducing tubulin assembly overcome tumoural cell resistances.
Matesanz R, Trigili C, Rodríguez-Salarichs J, Zanardi I, Pera B, Nogales A, Fang WS, Jímenez-Barbero J, Canales A, Barasoain I, Ojima I, Díaz JF. Matesanz R, et al. Among authors: pera b. Bioorg Med Chem. 2014 Sep 15;22(18):5078-90. doi: 10.1016/j.bmc.2014.05.048. Epub 2014 Jun 19. Bioorg Med Chem. 2014. PMID: 25047938 Free article.
New interfacial microtubule inhibitors of marine origin, PM050489/PM060184, with potent antitumor activity and a distinct mechanism.
Pera B, Barasoain I, Pantazopoulou A, Canales A, Matesanz R, Rodriguez-Salarichs J, García-Fernandez LF, Moneo V, Jiménez-Barbero J, Galmarini CM, Cuevas C, Peñalva MA, Díaz JF, Andreu JM. Pera B, et al. ACS Chem Biol. 2013 Sep 20;8(9):2084-94. doi: 10.1021/cb400461j. Epub 2013 Aug 1. ACS Chem Biol. 2013. PMID: 23859655
Mechanism of action of the cytotoxic macrolides amphidinolide X and J.
Trigili C, Pera B, Barbazanges M, Cossy J, Meyer C, Pineda O, Rodríguez-Escrich C, Urpí F, Vilarrasa J, Díaz JF, Barasoain I. Trigili C, et al. Among authors: pera b. Chembiochem. 2011 May 2;12(7):1027-30. doi: 10.1002/cbic.201100042. Epub 2011 Apr 15. Chembiochem. 2011. PMID: 21500335 No abstract available.
23 results